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Tongue Spindle Cell Rhabdomyosarcoma: A Rare Case Report and Literature Review

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Abstract

Rhabdomyosarcoma (RMS) is a malignant soft tissue neoplasm with its origin in the skeletal muscle and is extremely rare in adults. By the World Health Organization (WHO), a new variant of RMS has been classified, i.e. the spindle cell (Sc) and sclerosing (S) RMS. While the Sc-RMS shows intersecting fascicles of nonpleomorphic spindle cells, the S-RMS is characterized by a marked hyalinization in a pseudovascular growth pattern associated with round-to-spindled tumour cells. According to the analysed data, the Sc/S-RMS variant has a worse outcome than other variants. The new classification of the Sc/S-RMS variant is valuable to the clinical practice. There are not many oral Sc/S-RMS cases reported. The aim of this paper is to demonstrate that an early diagnosis, an adequate treatment and a multidisciplinary approach have a positive effect on the prognosis of the patient. In this study, we analyse a new case of Sc-RMS variant in a young adult with an early diagnosis and a favourable outcome as a result of an appropriated multidisciplinary treatment: early surgery, radiotherapy and chemotherapy treatment.

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Authors and Affiliations

  1. Oral and Maxillofacial Department, Miguel Servet University Hospital, Paseo Isabel La Católica, nº 1-3, 50009, Zaragoza, Spain

    Ursula M. Jariod–Ferrer, Bianca Pantilie, María V. Simon Sanz, Leire Esparza Lasaga, Marina A. Gavin–Clavero & Elena Delso-Gil

  2. Pathological Anathomy Department, Miguel Servet University Hospital, Paseo Isabel La Católica nº 1-3, Zaragoza, Spain

    Miguel Angel Trigo-Cebrian

  3. Medical Oncology Department, Miguel Servet University Hospital, Paseo Isabel La Católica nº 1-3, 50009, Zaragoza, Spain

    Javier Martinez-Trufero

Authors
  1. Ursula M. Jariod–Ferrer
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  2. Miguel Angel Trigo-Cebrian
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  3. Bianca Pantilie
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  4. María V. Simon Sanz
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  5. Leire Esparza Lasaga
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  6. Marina A. Gavin–Clavero
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  7. Elena Delso-Gil
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  8. Javier Martinez-Trufero
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Correspondence to Ursula M. Jariod–Ferrer.

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Jariod–Ferrer, U.M., Trigo-Cebrian, M.A., Pantilie, B. et al. Tongue Spindle Cell Rhabdomyosarcoma: A Rare Case Report and Literature Review. J. Maxillofac. Oral Surg. 20, 464–469 (2021). https://doi.org/10.1007/s12663-020-01447-3

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  • DOI: https://doi.org/10.1007/s12663-020-01447-3

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