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A Comparative Study of Platelet-Rich Fibrin and Platelet-Rich Fibrin with Hydroxyapatite to Promote Healing of Impacted Mandibular Third Molar Socket

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Abstract

Aim

The purpose of this study was to compare the efficacy of platelet-rich fibrin (PRF) and platelet-rich fibrin (PRF) with hydroxyapatite (HA) on postoperative pain, swelling, soft tissue healing and osseous regeneration in mandibular third molar extraction socket in human patient.

Materials and Methods

This prospective study included total 40 patients who reported to the Department of Oral and Maxillofacial Surgery (OMFS), Teerthanker Mahaveer Dental College and Research Centre (TMDC&RC), Moradabad (U.P.). Twenty patients each in both the groups of PRF and PRF with HA were included for the management of impacted mandibular 3rd molar extraction sockets and were evaluated for effectiveness. Evaluation was done on the basis of following parameters pain and swelling at time interval of 1st, 3rd, 7th day, soft tissue healing at time interval of 3rd, 7th, 14th day and osseous regeneration at time intervals of 1st, 3rd, 6th month postoperatively.

Results

Pain and swelling were less in the PRF with HA group when compared to PRF group. Soft tissue healing was better in the PRF with HA group compared to the PRF group. The result of the study shows rapid bone regeneration in the extraction socket treated with the PRF with HA group when compared with the PRF group. Also there was less postoperative discomfort in the PRF with HA-treated group.

Conclusion

PRF a mitogenic promoter together with a bone graft forms a scaffolding, promotes early healing thus being creating beneficial for the patient and is also economic.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, 244001, India

    Shamshad Alam & K. V. Arun Kumar

  2. Department of Oral and Maxillofacial Surgery, ITS-CDSR, Muradnagar, Ghaziabad, Uttar Pradesh, 201206, India

    Gagan Khare

Authors
  1. Shamshad Alam
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  2. Gagan Khare
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  3. K. V. Arun Kumar
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Corresponding author

Correspondence to Shamshad Alam.

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All authors declare that they have no conflicts of interest.

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Informed consent was obtained from all the participants.

Ethical Approval

Ethical clearance for this study was taken from the Ethical committee of TMU, Moradabad. No animals were included in the study.

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Alam, S., Khare, G. & Arun Kumar, K.V. A Comparative Study of Platelet-Rich Fibrin and Platelet-Rich Fibrin with Hydroxyapatite to Promote Healing of Impacted Mandibular Third Molar Socket. J. Maxillofac. Oral Surg. 21, 608–615 (2022). https://doi.org/10.1007/s12663-020-01417-9

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  • DOI: https://doi.org/10.1007/s12663-020-01417-9

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