Abstract
This cross-sectional study aims to determine the prevalence of IgM and IgG anti-T. gondii antibodies and the associated risk factors among childbearing age women referring to counseling centers before marriage in Kerman city, southeast of Iran. Totally, 300 serum samples were collected from women referred to Central Laboratory for Marriage Consultation in Kerman city were screened for IgG and IgM anti-T. gondii antibodies by enzyme linked immunosorbent assay (ELISA). Out of the 300 serum samples, 38 (12.6 %) tested seropositive for anti-T. gondii antibodies; 31 (10.3 %) samples tested seropositive for only IgG antibody, 1 (0.33 %) tested seropositive for both IgM and IgG and 6 (2.0 %) were positive for IgM antibody alone. Statistical analyses also indicated that seroprevalence of anti-T. gondii antibodies increased with age (p < 0.05). Moreover, some risk factors such as, living in rural regions, contact with cats, raw/half-cooked meat consumption, and agricultural activities were significantly (p < 0.05) related to T. gondii seropositivity. The findings revealed that more than three-quarters of the childbearing age women studied in the present investigation are susceptible to infection during pregnancy. Thus, by adopting correct and improved practices we can improve their living conditions, and prevent infection and awareness and control of pathogens associated with disease is recommended.
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Alvarado-Esquivel C, Mercado-Suarez MF, Rodríguez-Briones A, Fallad-Torres L, Ayala-Ayala JO, Nevarez-Piedra LJ et al (2007) Seroepidemiology of infection with Toxoplasma gondii in healthy blood donors of Durango, Mexico. BMC Infect Dis 7:75–81
Borna S, Shariat M, Fallahi M, Janani L (2013) Prevalence of immunity to toxoplasmosis among Iranian childbearing age women: systematicreview and meta-analysis. Iran J Reprod Med 11(11):861–868
Derouin F, Pelloux H (2008) Prevention of toxoplasmosis in transplant patients. Clin Microbiol Infect 14:1089–1101
Dubey JP, Beattie CP (1998) Toxoplasmosis of animals and man. CRC, Boca Raton, pp 1–220
Falah E, Majidi J, Navazesh R, Kushavar H, Mahdipourzare N (2005) An epidemiological study of toxoplasma infection among high-school girls in Jolfa. J Reprod Infertil 6:261–269 (In Persian)
Fatta A, Elahi SR, Berenji F, Zarea R, Ghaboli Shahrodi MJ, Ashrafi Abyane H (2001) Evaluation of immunofluorescence antibody (IFA) & immunoperoxidase (IP) tests among 200 pregnant women for Toxoplasmosis. J Mashhad Univ Med Sci 44:16–21
Haghdoost AA, Sadeghirad B, Hajarizadeh B, Mirzazadeh A (2007) The application of systematic review and meta-analysis concepts in summarizing the findings of observational studies. Iran J Psychiatry 2:132–136
Hill D, Dubey J (2002) Toxoplasma gondii: transmission, diagnosis and prevention. Clin Microb Infect 8(10):634–640
Khazaei HA, Bokaeian M, Javadimehr M, Soleimani GR, Khazaei A, Narouie B et al (2012) Seroepidemiology evaluation of Toxoplasma IgG values in women at their marriage age and pathogenesis factors. Life Sci J 9(4):185–190
Kravetz J (2013) Congenital toxoplasmosis. BMJ Clin Evid 29:pii: 0906
Mahmoudvand H, Saedi Dezaki E, Soleimani S, Baneshi MR, Kheirandish F, Ezatpour B, Zia-ali N (2015) Seroprevalence and risk factors of Toxoplasma gondii infection among healthy blood donors in southeast of Iran. Parasite Immunol 37(7):362–367
Robert-Gangneux F, Darde ML (2012) Epidemiology of and diagnostic strategies for toxoplasmosis. Clin Microbiol Rev 2012(25):264–296
Signorini L, Gulletta M, Coppini D et al (2007) Fatal disseminated toxoplasmosis during primary HIV infection. Curr HIV Res 5:273–274
Sukthana Y (2006) Toxoplasmosis: beyond animals to humans. Trends Parasitol 22:137–142
Youssefi MR, Sefidgar AA, Mostafazadeh A, Omran SM (2007) Serologic evaluation of toxoplasmosis in matrimonial women in Babol, Iran. Pak J Biol Sci 10(9):1550–1552
Acknowledgments
This study was supported by Vice Chancellor for Research, Kerman University of Medical Sciences (Project No. 93/109) (Kerman, Iran). We would like to thank Dr. Sharifi and Mr. Kamiabi for data collection.
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Tavakoli Kareshk, A., Keyhani, A., Asadi, A. et al. Seroprevalence of Toxoplasma gondii infection among childbearing age women in Kerman city, southeastern Iran. J Parasit Dis 40, 1544–1547 (2016). https://doi.org/10.1007/s12639-015-0724-7
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DOI: https://doi.org/10.1007/s12639-015-0724-7