Editorial
The next step in improving (semi-)quantitative MPI PET

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Background

Myocardial blood flow (MBF) quantification with PET results in an improved risk assessment of coronary artery disease (CAD) in addition to semi-quantitative myocardial perfusion imaging.1 A decrease in the myocardial flow reserve (MFR, MBF in stress/MBF in rest) or an increasing area of perfusion deficits results in a higher risk on cardiac mortality, as shown in Figure 1. To be able to quantify MBF, tracer uptake in the left ventricle and the myocardium during the scan has to be calculated

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