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Takayasu’s arteritis associated with Crohn’s disease treated with infliximab

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Abstract

A 23-year-old woman presented with fever, diarrhea, bloody stools, and arthralgia that did not improve despite previous treatments and was diagnosed with Crohn’s disease. Remission was achieved after the introduction of infliximab, nutritional therapy, and 5-aminosalicylic acid treatment. However, the patient’s blood sedimentation rate remained elevated without symptom recurrence, except for abdominal pain in the following year. Aortic wall thickening in the thoracic descending aorta was also observed on computed tomography. Accumulation in the thoracic descending aorta and abdominal aorta was confirmed using positron emission tomography–computed tomography. The patient was diagnosed with Takayasu’s arteritis. The patient’s abdominal symptoms resolved, and her blood sedimentation rate normalized after steroid administration.

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Acknowledgements

The authors thank the reviewers for comments on an earlier version of this paper.

Author information

Authors and Affiliations

  1. Department of Gastroenterology, Mito Kyodo General Hospital, 3-2-7 Miya-Machi, Mito, Ibaraki, 310-0015, Japan

    Hiroyuki Ariga, Takeshi Ojima, Satoshi Suzuki, Kenta Okada & Junya Kashimura

  2. Department of Rheumatology, Mito Kyodo General Hospital, Mito, Japan

    Yusuke Chino

Authors
  1. Hiroyuki Ariga
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  2. Yusuke Chino
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  3. Takeshi Ojima
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  4. Satoshi Suzuki
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  5. Kenta Okada
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  6. Junya Kashimura
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by HA. The first draft of the manuscript was written by HA and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Hiroyuki Ariga.

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Research involving human participants and/or animals

All the procedures performed in the study were in accordance with the ethical standards of the institutional reviews board/international ethics committee for each center and with the 1964 Helsinki Declaration and its later ammendments.

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Ariga, H., Chino, Y., Ojima, T. et al. Takayasu’s arteritis associated with Crohn’s disease treated with infliximab. Clin J Gastroenterol 17, 281–285 (2024). https://doi.org/10.1007/s12328-023-01904-9

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  • DOI: https://doi.org/10.1007/s12328-023-01904-9

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