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Rare Association of Coeliac Disease with Aplastic Anaemia: Report of a Case from India

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Coeliac disease is a systemic autoimmune disorder with major intestinal manifestations. It has multiple hematologic associations including anaemia (mostly due to iron, folate and/or vitamin B12 malabsorption), other cytopenias, coagulation abnormalities, hyposplenism, IgA deficiency and lymphomas. Aplastic anaemia has however, only rarely been described with celiac disease in published literature. We here present a case of atypical coeliac disease in a 40 year male Indian patient, with insignificant gastrointestinal symptoms, presenting with aplastic anaemia manifested by pancytopenia with hypocellular bone marrow. On gluten free diet, his symptoms like weakness, fatigue and malaise were relieved—blood and platelet transfusion requirement also diminished.

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Authors and Affiliations

  1. Department of Tropical Medicine, Calcutta School of Tropical Medicine, Kolkata, India

    Ayan Basu, Yogiraj Ray, Pratik Bowmik, Mehebubar Rahman & Rama Prosad Goswami

  2. Department of Haematology, Calcutta School of Tropical Medicine, Kolkata, India

    Nidhi Dikshit & Rama Prosad Goswami

  3. 46/27A, Becharam Chatterjee Road, Behala, Kolkata, West Bengal, 700034, India

    Ayan Basu

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  1. Ayan Basu
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  2. Yogiraj Ray
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  3. Pratik Bowmik
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  4. Mehebubar Rahman
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  5. Nidhi Dikshit
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  6. Rama Prosad Goswami
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Correspondence to Ayan Basu.

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Basu, A., Ray, Y., Bowmik, P. et al. Rare Association of Coeliac Disease with Aplastic Anaemia: Report of a Case from India. Indian J Hematol Blood Transfus 30 (Suppl 1), 208–211 (2014). https://doi.org/10.1007/s12288-014-0331-2

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  • DOI: https://doi.org/10.1007/s12288-014-0331-2

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