Abstract
By various chromatographic methods, two new phenylpropanoid esters of sucrose named hidropiperosides A (1) and B (2), and three known compounds as vanicosides A (3), B (4), and E (5) were isolated from the methanolic extract of the whole plant of Polygonum hydropiper L. (Polygonaceae). Their structures were elucidated by extensive spectroscopic methods including 1D-and 2D-NMR experiments, as well as ESI-MS analysis. All the isolated compounds were tested for their antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay system. Among them, compounds 2 and 3 showed significant antioxidant activity with their SC50 values of 23.4 and 26.7 μg/mL, respectively.
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Barnes, C. S. and Loder, J. W., Structure of polygodial: A new sesquiterpene dialdehyde from Polygonum hydropiper. Aust. J. Chem., 15, 322–327 (1962).
Brown, L. L., Larson, S. R., and Sneden, A. T., Vanicosides C-F, New phenylpropanoid glycosides from Polygonum pensylvanicum. J. Nat. Prod., 61, 762–766 (1998).
Fukuyama, Y., Sato, T., Miura, I., and Asakawa, Y., Drimanetype sesqui-and norsesquiterpenoids from Polygonum hydropiper. Phytochemistry, 24, 1521–1524 (1985).
Fukuyama, Y., Sato, T., Miura, I., Asakawa, Y., and Takemoto, T., Polygonum, A novel coumaryl glycoside from the root of Polygonum hydropiper. Phytochemistry, 22, 549–552 (1983).
Haraguchi, H., Hashimoto, K., and Yagi, A., Antioxidative substances in leaves of Polygonum hydropiper. J. Agric. Food. Chem., 40, 1349–1351 (1992).
Haraguchi, H., Ohmi, I., Sakai, S., Fukuda, A., Toihara, Y., Fujimoto, T., Okamura, N., and Yagi, A., Effect of Polygonum hydropiper sulfated flavonoids on lens aldose reductase and related enzymes. J. Nat. Prod., 59, 443–445 (1996).
Lee J. S., Kim H. J., Park H. and Lee Y. S., New diarylheptanoids from the stem of Carpinus cordata. J. Nat. Prod., 65, 1367–1370 (2002).
Li, S. Y., Fuchino, H., Kawahara N., Sekia S., and Satake M., New phenolic constituents from Smilax bracteata. J. Nat. Prod., 65, 262–266 (2002).
Loi, D. T., The glossary of Vietnamese medicinal plants and items. Hanoi Medicine Publishing House, Hanoi, Vietnam, 283–284 (2000).
Miyazawa, M. and Tamura, N., Inhibitory compound of tyrosinase activity from the sprout of Polygonum hydropiper L. (Benitade). Biol. Pharm. Bull., 30, 595–597 (2007).
Takasaki, M., Kuroki, S., Kozuka, M., and Konoshima, T., New phenylpropanoid esters of sucrose from Polygonum lapathifolium. J. Nat. Prod., 64, 1305–1308 (2001).
Zhao, F. P., Dieter, S., Alfred, B., Ramanathan, S., Ngoh K. G., Tet F. C., Swee N. T., and Lian S. C., Antioxidant flavonoids from leaves of Polygonum hydropiper L. Phytochemistry, 62, 219–228 (2003).
Zimmermann, M. L. and Sneden A. T., Vanicosides A and B, protein kinase C inhibitors from Polygonum pensylvanicum. J. Nat. Prod., 57, 236–242 (1994).
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Kiem, P.V., Nhiem, N.X., Cuong, N.X. et al. New phenylpropanoid esters of sucrose from Polygonum hydropiper and their antioxidant activity. Arch. Pharm. Res. 31, 1477–1482 (2008). https://doi.org/10.1007/s12272-001-2133-y
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DOI: https://doi.org/10.1007/s12272-001-2133-y