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Maßgeschneidertes Genom — Designer-Nukleasen im Einsatz

  • 20 Jahre BIOspektrum · Highlights Aus Der Wissenschaft
  • Gentechnologie
  • Published:
BIOspektrum Aims and scope

Abstract

Designer nucleases are artificial proteins for the precise modification of complex genomes. The most commonly used platforms are zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas system. These powerful tools greatly facilitate the generation of plant and animal models for basic research, and harbor an enormous potential for applications in biotechnology and regenerative medicine.

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Authors and Affiliations

  1. Institut für Zell- und Gentherapie, Universitätsklinikum Freiburg, Engesserstraße 4, D-79106, Freiburg, Deutschland

    Christien Bednarski & Toni Cathomen

Authors
  1. Christien Bednarski
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  2. Toni Cathomen
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Correspondence to Toni Cathomen.

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Bednarski, C., Cathomen, T. Maßgeschneidertes Genom — Designer-Nukleasen im Einsatz. Biospektrum 21, 22–24 (2015). https://doi.org/10.1007/s12268-015-0528-4

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  • DOI: https://doi.org/10.1007/s12268-015-0528-4

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