Abstract
The bacterial flagellum is a molecular nanomachine used for locomotion. In Salmonella, the assembly of the flagellum is a highly coordinated and regulated process. On top of a complex regulatory network resides the flagellar master operon flhDC. Many environmental signals are integrated on the level of flhDC expression, including transcriptional cross talk between the virulence and flagellar systems that contributes to the correct spatiotemporal expression of the different virulence factors during the infection process.
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Hanna M. Singer Jahrgang 1984. 2004–2009 Biologiestudium an der Universität Konstanz. 2009 Diplomarbeit an der University of Utah, Salt Lake City, USA. 2010–2013 Forschungsaufenthalt an der University of Utah, Salt Lake City, USA und der Université de Fribourg, Schweiz. Seit 2013 Wissenschaftliche Mitarbeiterin am Helmholtz-Zentrum für Infektionsforschung in Braunschweig. Seit 2010 Promotion an der Universität Konstanz und seit 2013 wissenschaftliche Mitarbeiterin am Helmholtz-Zentrum für Infektionsforschung in Braunschweig.
Marc Erhardt Jahrgang 1981. 2002–2006 Biologiestudium an den Universitäten Ulm und Konstanz. 2006 Diplomarbeit an der University of Utah, Salt Lake City, USA. 2011 Promotion an der Universität Konstanz. 2011–2013 Postdoktorand an der Université de Fribourg, Schweiz. Seit 2013 Leiter der Nachwuchsgruppe Infektionsbiologie von Salmonellen am Helmholtz-Zentrum für Infektionsforschung in Braunschweig.
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Singer, H.M., Erhardt, M. Regulation, Aufbau und Funktion einer bakteriellen Nanomaschine. Biospektrum 20, 500–502 (2014). https://doi.org/10.1007/s12268-014-0470-x
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DOI: https://doi.org/10.1007/s12268-014-0470-x