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Bem46-Homologe: bekannte Proteine mit unbekannter Funktion

known unknown genes

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Abstract

The bud emergence (BEM) 46 proteins are evolutionarily conserved members of the α/β-hydrolase super family. The exact function(s) of these proteins remains unknown. Vegetative hyphae, perithecia and ascospores of Neurospora crassa RNAi and over-expressing transformants develop normally, but hyphal germination from ascospores is impaired. The protein is localized in the perinuclear endoplasmatic reticulum and also forms spots near to the plasma membrane. One human paralog appears to be responsible for a genetic disorder.

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Authors and Affiliations

  1. Abteilung Botanische Genetik und Molekularbiologie, Universität Kiel, Kiel, Germany

    Krisztina Kolláth-Leiβ & Frank Kempken

  2. Christian-Albrechts-Universität zu Kiel Abteilung Botanische Genetik und Molekularbiologie, Botanisches Institut und Botanischer Garten, Olshausenstraße 40, D-24098, Kiel, Germany

    Frank Kempken

Authors
  1. Krisztina Kolláth-Leiβ
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  2. Frank Kempken
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Correspondence to Frank Kempken.

Additional information

Krisztina Kolláth-Leiß 1999–2002 Studium der Biologie, Eötvös Loránd Universität, Budapest, Ungarn. 2003–2008 Studium der Biologie an der Universität zu Kiel. Seit 2008 Dissertation bei Prof. Dr. F. Kempken.

Frank Kempken 1980–1985 Studium der Biologie an der Universität Bochum, 1988 Promotion bei Prof. Dr. Dr. h. c. mult. K. Esser, 1989–1990 Postdoc bei Prof. Dr. D. Pring, University of Florida, USA.1996 Habilitation, 1996–2001 Hochschuldozent an der Universität Bochum. Seit 2001 Professur für Botanische Genetik und Molekularbiologie an der Universität zu Kiel, seit 2011 Vizepräsident der Gesellschaft für Genetik.

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Kolláth-Leiβ, K., Kempken, F. Bem46-Homologe: bekannte Proteine mit unbekannter Funktion. Biospektrum 18, 251–253 (2012). https://doi.org/10.1007/s12268-012-0170-3

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  • DOI: https://doi.org/10.1007/s12268-012-0170-3

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