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Adipose Tissue-derived Stem Cells: The Friendly Side of a Classic Cardiovascular Foe

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Abstract

Recently, the existence of a population of stem cells located in the adipose tissue has been observed. Adipose-derived stem cells are able to differentiate into multiple cell lineages including cardiac myocytes. Hence, adipose-derived cells are emerging as a new source of adult stem cells for cardiovascular repair. In this review, we discuss the basic principles of adipose-derived stem cells (types and characteristics, obtention processes, immunophenotypic characterization, and cell potency), the initial experimental studies, and the currently ongoing clinical trials.

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Authors and Affiliations

  1. Cardiology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    Ricardo Sanz-Ruiz, Marta Domínguez Muñoa, Ingrid Ludwig Martín, Radoslaw Parma, Pedro L. Sánchez Fernández & Francisco Fernández-Avilés

  2. Cell Processing Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    María Eugenia Fernández Santos

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  1. Ricardo Sanz-Ruiz
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  2. María Eugenia Fernández Santos
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  3. Marta Domínguez Muñoa
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  4. Ingrid Ludwig MartĂ­n
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  6. Pedro L. Sánchez Fernández
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Correspondence to Francisco Fernández-Avilés.

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Sanz-Ruiz, R., Fernández Santos, M.E., Domínguez Muñoa, M. et al. Adipose Tissue-derived Stem Cells: The Friendly Side of a Classic Cardiovascular Foe. J. of Cardiovasc. Trans. Res. 1, 55–63 (2008). https://doi.org/10.1007/s12265-007-9006-9

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  • DOI: https://doi.org/10.1007/s12265-007-9006-9

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