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Perianal Paget’s Disease; Surgery and Non-surgical Interventions, Untreated Patient: a Report of Two Cases

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Abstract

Perianal Paget’s disease (PPD) is a rare intraepithelial adenocarcinoma. The clinical appearance of PPD may be confused with dermatitis and fungal infections of the skin, resulting in delayed diagnosis, sometimes for years. It may also be associated with secondary malignancies. Surgery and non-surgical methods such as radiotherapy, immunomodulating drugs, and chemotherapy are used in the treatment of PPD. In this case report, two patients with PPD are presented; the first was treated with surgical excision and radiotherapy and the second did not accept surgical or medical therapy. Although the lesion deepened and expanded towards adjacent structures, no secondary malignancy or metastasis was observed.

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Authors and Affiliations

  1. Department of General Surgery, Section of Gastroenterological Surgery, Ankara Dışkapı Yıldırım Beyazıt Research and Training Hospital, Ankara, Turkey

    Ümit Özdemir

  2. Department of General Surgery, Eskişehir Osmangazi University Medical School, Eskişehir, Turkey

    Mustafa Salış

  3. Department of General Surgery, Section of Gastroenterological Surgery, Eskişehir Osmangazi University Medical School, Eskişehir, Turkey

    İlter Özer

  4. Department of General Surgery, Istanbul Aydin University, Florya WM Medical Park Hospital, Istanbul, Turkey

    Bülent Ünal

Authors
  1. Ümit Özdemir
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  2. Mustafa Salış
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  3. İlter Özer
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  4. Bülent Ünal
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Correspondence to Ümit Özdemir.

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Özdemir, Ü., Salış, M., Özer, İ. et al. Perianal Paget’s Disease; Surgery and Non-surgical Interventions, Untreated Patient: a Report of Two Cases. Indian J Surg 85, 169–174 (2023). https://doi.org/10.1007/s12262-022-03376-6

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  • DOI: https://doi.org/10.1007/s12262-022-03376-6

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