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Smart Stimuli-Responsive Polylactic Acid-Hydrogel Fibers Produced via Electrospinning

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Abstract

In this research we propose a new type of smart microfibers, distinguished by moisture management and proactive temperature and pH controlled release activity. Hydrogel with submicron-sized particles based on poly(N-isopropylacrylamide) (poly-NiPAAm) and chitosan (PNCS hydrogel) was incorporated into the structure of poly(lactic acid) (PLA) microfibers using the electrospinning technique. Composites with different PLA to PNCS hydrogel ratios were prepared, and the chemical and morphological properties of the samples were studied using SEM, FT-IR and Raman mapping. Additionally, the moisture management properties, which were provided by the temperature and pH-related phase change transition of the incorporated PNCS hydrogel, were studied by determining the temperature-related static contact angle, thin-layer wicking, moisture content and pH-related water uptake. The loading and release abilities of the incorporated PNCS hydrogel were studied using fluorescent microscopy. The increased concentration of the PNCS hydrogel in spinning solutions resulted in greater variations in fiber thickness and deterioration of the mechanical properties of the fibers; thus, the highest concentration of the PNCS hydrogel that could be incorporated within the fibers was found to be 20 % of the spinning mass. The composite sample showed temperature and pH responsiveness, a successful fluorescent-dye loading ability and its controlled release at predetermined conditions.

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Acknowledgements

This work was supported by the Slovenian Research Agency (Program P2-0213, Infrastructural Centre RIC UL-NTF, grant for the doctoral student, D.Š. and Program P2-0207 in ARRS grant J3-8201).

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Authors and Affiliations

  1. Department of Textiles, Graphic Arts and Design, Faculty of Natural Sciences and Engineering, University of Ljubljana, Ljubljana, 1000, Slovenia

    Danaja Štular, Jožef Medved, Barbara Simončič & Brigita Tomšič

  2. Institute of Textile Technology, RWTH Aachen University, Aachen, 52074, Germany

    Magnus Kruse, Laura Kreinest, Thomas Gries & Andreas Blaeser

  3. Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, 1001, Slovenia

    Vera Župunski

  4. National Institute of Chemistry, Ljubljana, 1000, Slovenia

    Ivan Jerman

Authors
  1. Danaja Štular
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  2. Magnus Kruse
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  3. Vera Župunski
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  4. Laura Kreinest
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  5. Jožef Medved
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  6. Thomas Gries
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  7. Andreas Blaeser
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  8. Ivan Jerman
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  9. Barbara Simončič
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  10. Brigita Tomšič
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Correspondence to Brigita Tomšič.

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Štular, D., Kruse, M., Župunski, V. et al. Smart Stimuli-Responsive Polylactic Acid-Hydrogel Fibers Produced via Electrospinning. Fibers Polym 20, 1857–1868 (2019). https://doi.org/10.1007/s12221-019-9157-8

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  • DOI: https://doi.org/10.1007/s12221-019-9157-8

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