Skip to main content
SpringerLink
Log in

An evaluation of peripherally inserted central venous catheters for children with cancer requiring long-term venous access

  • Original Article
  • Published:
International Journal of Hematology Aims and scope Submit manuscript

Abstract

Long-term venous access is essential when treating malignant diseases. We reviewed our experience with peripherally inserted central venous catheters (PICC) in children suffering from various malignancies with regard to catheter life, reasons for removal, and complications. Ninety-three PICCs were inserted in 78 children. Median catheter life was 162 days (range 6–575 days) with a total of 16,266 catheter days. Seventy-five PICCs (80.6%) had been placed until the elective removal or patients’ death, whereas 18 PICCs (19.4%) were removed due to PICC-related complications; a rate of 1.11 per 1,000 catheter days. Complications requiring removal of PICCs included infection (n = 12), occlusion (n = 3), dislodgement (n = 2), and phlebitis (n = 1) with rates of 0.74, 0.18, 0.12 and 0.06 per 1,000 catheter days, respectively. We conclude that PICC provides reliable long-term intravenous access in children suffering from malignancies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Chung DH, Ziegler MM. Central venous catheter access. Nutrition. 1998;14:119–23.

    Article  CAS  PubMed  Google Scholar 

  2. Crowley JJ. Vascular access. Tech Vasc Interv Radiol. 2003;6:176–81.

    Article  PubMed  Google Scholar 

  3. Ryder MA. Peripheral access options. Surg Oncol Clin N Am. 1995;4:395–427.

    CAS  PubMed  Google Scholar 

  4. Cardella JF, Cardella K, Bacci N, Fox PS, Post JH. Cumulative experience with 1, 273 peripherally inserted central catheters at a single institution. J Vasc Interv Radiol. 1996;7:5–13.

    Article  CAS  PubMed  Google Scholar 

  5. Walshe LJ, Malak SF, Eagan J, Sepkowitz KA. Complication rates among cancer patients with peripherally inserted central catheters. J Clin Oncol. 2002;20:3276–81.

    Article  PubMed  Google Scholar 

  6. Yap YS, Karapetis C, Lerose S, Iyer S, Koczwara B. Reducing the risk of peripherally inserted central catheter line complications in the oncology setting. Eur J Cancer Care. 2006;15:342–7.

    Article  Google Scholar 

  7. Matsuzaki A, Suminoe A, Koga Y, Hatano M, Hattori S, Hara T. Long-term use of peripherally inserted central venous catheters for cancer chemotherapy in children. Support Care Cancer. 2006;14:153–60.

    Article  PubMed  Google Scholar 

  8. Shen G, Gao Y, Wang Y, Mao B, Wang X. Survey of the long-term use of peripherally inserted central venous catheters in children with cancer: experience in a developing country. J Pediatr Hematol Oncol. 2009;31:489–92.

    Article  PubMed  Google Scholar 

  9. Abedin S, Kapoor G. Peripherally inserted central venous catheters are a good option for prolonged venous access in children with cancer. Pediatr Blood Cancer. 2008;51:251–5.

    Article  PubMed  Google Scholar 

  10. Donowitz GR, Maki DG, Crnich CJ, Pappas PG, Rolston KV. Infections in the neutropenic patient—new views of an old problem. Hematology Am Soc Hematol Educ Program 2001; 113–39.

  11. Bethune K, Allwood M, Grainger C, Wormleighton C. Use of filters during the preparation and administration of parenteral nutrition: position paper and guidelines prepared by a British pharmaceutical nutrition group working party. Nutrition. 2001;17:403–8.

    Article  CAS  PubMed  Google Scholar 

  12. Ball PA. Intravenous in-line filters: filtering the evidence. Curr Opin Clin Nutr Metab Care. 2003;6:319–25.

    PubMed  Google Scholar 

  13. O’Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, et al. Guidelines for the prevention of intravascular catheter-related infections. Infect Control Hosp Epidemiol. 2002;23:759–69.

    Article  PubMed  Google Scholar 

  14. Friedland G. Infusion-related phlebitis—is the in-line filter the solution? N Engl J Med. 1985;312:113–5.

    Article  CAS  PubMed  Google Scholar 

  15. Fratino G, Molinari AC, Parodi S, Longo S, Saracco P, Castagnola E, et al. Central venous catheter-related complications in children with oncological/hematological diseases: an observational study of 418 devices. Ann Oncol. 2005;16:648–54.

    Article  CAS  PubMed  Google Scholar 

  16. Cesaro S, Tridello G, Cavaliere M, Magagna L, Gavin P, Cusinato R, et al. Prospective, randomized trial of two different modalities of flushing central venous catheters in pediatric patients with cancer. J Clin Oncol. 2009;27:2059–65.

    Article  PubMed  Google Scholar 

Download references

Acknowledgment

The authors thank Dr. Peter Olley (Professor Emeritus, University of Alberta, Alberta, Canada) for help with the manuscript preparation.

Author information

Authors and Affiliations

  1. Department of Pediatrics, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan

    Naoki Hatakeyama, Tsukasa Hori, Masaki Yamamoto, Nobuo Mizue, Natsuko Inazawa, Keita Igarashi, Hiroyuki Tsutsumi & Nobuhiro Suzuki

Authors
  1. Naoki Hatakeyama
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tsukasa Hori
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Masaki Yamamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Nobuo Mizue
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Natsuko Inazawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Keita Igarashi
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Hiroyuki Tsutsumi
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Nobuhiro Suzuki
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Naoki Hatakeyama.

About this article

Cite this article

Hatakeyama, N., Hori, T., Yamamoto, M. et al. An evaluation of peripherally inserted central venous catheters for children with cancer requiring long-term venous access. Int J Hematol 94, 372–377 (2011). https://doi.org/10.1007/s12185-011-0928-2

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12185-011-0928-2

Keywords

Search

Navigation