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The association of pagophagia with Helicobacter pylori infection in patients with iron-deficiency anemia

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Abstract

This study aimed to determine the relationship between pagophagia (compulsive ice eating) and H. pylori infection in patients with iron-deficiency anemia. We identified H. pylori infection using the 13C-urea breath test in 45 patients with iron-deficiency anemia (group 1) and 55 patients with iron-deficiency anemia and pagophagia (group 2). Subgroups for testing oral intestinal iron absorption were randomly assigned from both groups. These subgroups consisted of (a) 10 patients with iron-deficiency anemia, (b) 10 patients with iron-deficiency anemia and pagophagia, (c) 10 patients with iron-deficiency anemia, pagophagia, and H. pylori infection before the eradication of H. pylori and (d) subgroup c after eradication therapy. There was no difference in the rate of H. pylori infection in the iron-deficiency anemia groups, with or without pagophagia. Furthermore, oral intestinal iron absorption was not influenced by pagophagia and/or H. pylori infection. Pagophagia did not increase the risk of H. pylori infection in patients with iron-deficiency anemia. Pagophagia and H. pylori infection do not synergistically affect the development of intestinal iron absorption abnormalities.

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Authors and Affiliations

  1. Department of Family Medicine, Baskent University Faculty of Medicine, 06490, Ankara, Turkey

    Suheyl Asma

  2. Department of Hematology, Baskent University Faculty of Medicine, 06490, Ankara, Turkey

    Can Boga & Hakan Ozdogu

  3. Department of Gastroenterology, Baskent University Faculty of Medicine, 06490, Ankara, Turkey

    Ender Serin

  4. Department of Hematology, Baskent University Adana Teaching and Medical Research Center, Dadaloglu Mahallesi Serin Evler Sokak 39 No: 6 Yuregir, 01250, Adana, Turkey

    Can Boga

Authors
  1. Suheyl Asma
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  2. Can Boga
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  3. Hakan Ozdogu
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  4. Ender Serin
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Correspondence to Can Boga.

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Asma, S., Boga, C., Ozdogu, H. et al. The association of pagophagia with Helicobacter pylori infection in patients with iron-deficiency anemia. Int J Hematol 90, 28–32 (2009). https://doi.org/10.1007/s12185-009-0360-z

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  • DOI: https://doi.org/10.1007/s12185-009-0360-z

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