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Metastasizing Pleomorphic Adenoma Case Report and Review of the Literature

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Abstract

Pleomorphic adenoma (PA) is by far the most common salivary gland tumor. It is well known that PA can undergo malignant transformation. However, in rare occasions it can metastasize preserving its benign phenotype. Metastasizing pleomorphic adenoma (MPA) constitutes an extremely rare tumor. Here we are reporting an unusual MPA affecting the mandible that was preceded by a submandibular gland pleomorphic adenoma.

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Author information

Authors and Affiliations

  1. Advanced Oral and Maxillofacial Pathology Program, Department of Oral Diagnostic Sciences, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY, USA

    Rana Alshagroud

  2. Department of Oral and Maxillofacial Surgery School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY, USA

    Amandip Kamoh

  3. Department of Otolaryngology, School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA

    Saurin R. Popat

  4. Erie County Medical Center and Delaware Medical Group, Buffalo, NY, USA

    Saurin R. Popat

  5. Department of Pathology, School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA

    Margaret Brandwein-Weber

  6. Department of Oral Diagnostic Sciences, School of Dental Medicine, University at Buffalo, 355 Squire Hall, Buffalo, NY, 14214, USA

    Alfredo Aguirre

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  1. Rana Alshagroud
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Correspondence to Alfredo Aguirre.

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Alshagroud, R., Kamoh, A., Popat, S.R. et al. Metastasizing Pleomorphic Adenoma Case Report and Review of the Literature. Head and Neck Pathol 11, 487–493 (2017). https://doi.org/10.1007/s12105-017-0815-0

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  • DOI: https://doi.org/10.1007/s12105-017-0815-0

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