Avoid common mistakes on your manuscript.
To the Editor: We appreciate Finsterer J. for critical review and comments on our article published in IJP [1]. Regarding queries raised by the author [2], we would like to highlight our case. In our case we diagnosed as stroke like events (SLE) rather than stroke, due to involvement of multiple sites in non-vascular territory, less severity of the weakness, significant improvement in the power within few days of onset of the weakness, and normal magnetic angiography of the brain. We didn’t do other sequence of MRI of the brain and follow-up MRI of the brain due to financial constraints. This child was born out of third-degree consanguineous parentage; we did not do sanger sequencing of parents due to financial constraints. We mentioned molybdenum cofactor deficiency (MoCD) can mimic as hypoxic ischemic encephalopathy (HIE) radiologically and do not have HIE [3]. The hemiparesis was temporary since there was recovery at the time of discharge. The diet advised is a cysteine-restricted diet, which typically includes low protein intake with restriction of whole natural protein.
References
Markose AP, Gowda VK, Reddy VS, Srinivasan VM. Molybdenum cofactor deficiency (MoCD) masquerading as stroke-like episodes. Indian J Pediatr. 2023. https://doi.org/10.1007/s12098-023-05002-z.
Finsterer J. Molybdenum cofactor deficiency (MoCD) masquerading as stroke-like episodes: Correspondence. Indian J Pediatr. 2024. https://doi.org/10.1007/s12098-024-05046-9.
Yoganathan S, Sudhakar S, Thomas M, Kumar Dutta A, Danda S, Chandran M. Novel imaging finding and novel mutation in an infant with molybdenum cofactor deficiency, a mimicker of hypoxic-ischaemic encephalopathy. Iran J Child Neurol. 2018;12:107–12.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
None.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Gowda, V.K., Markose, A.P., Reddy, V.S. et al. Molybdenum Cofactor Deficiency (MoCD) Masquerading as Stroke Like Episodes: Authors’ Reply. Indian J Pediatr (2024). https://doi.org/10.1007/s12098-024-05047-8
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s12098-024-05047-8