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Public Health Implications of Obstructive Sleep Apnea Burden

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Abstract

Objective

To assess the implications of obstructive sleep apnea (OSA) burden among Indian children.

Methods

MonteCarlo simulations were performed in order to estimate the number of OSA related obesity cases among Indian children (1–14 y of age) and the number of cases of stroke, coronary heart disease (CHD) and type 2 diabetes, considered as main adverse outcomes of OSA related childhood obesity, according to untreated and treated [adenotonsillectomy (AT) alone and AT associated to continuous positive airway pressure (CPAP)] pediatric OSA. Data used to perform MonteCarlo simulations were derived from a review about current literature exploring OSA related obesity.

Results

The analysis on the number of adverse outcomes according to treated and untreated obesity related to OSA showed that treatments reduce the number of obesity cases, resulting in a great reduction of the amount of stroke, CHD and type 2 diabetes cases. However, the cost for treating adverse outcome was higher in patients treated for obesity related to OSA compared to those not receiving any treatment.

Conclusions

The reduction in the number of adverse outcomes due to treatment of obesity related OSA implicates the urgent need for public health policies in providing screening for OSA among children population: an early detection and a consequently prompt reaction to pediatric OSA could improve the burden of OSA related obesity.

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Contributions

IB, AG, DG Designed the study; IB, GL Wrote the manuscript; DG, GL Performed the statistical analysis; KN, SB, RR, GS critically revised the manuscript and contributed to the discussion. All authors contributed to results interpretation, read and approved the final manuscript. IB will act as guarantor for this paper.

Conflict of Interest

None.

Source of Funding

This work is partially supported by an unrestricted grant from the Italian Ministry of Foreign Affairs, Directorate General for Country Promotion, and from Prochild ONLUS (Italy).

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Authors and Affiliations

  1. Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Via Loredan, 18, 35121, Padova, Italy

    Ileana Baldi, Giulia Lorenzoni & Dario Gregori

  2. Department of Otorhinolaryngology (ENT), Maulana Azad Medical College, New Delhi, India

    Achal Gulati

  3. Madras ENT Research Foundation (P) Ltd. (MERF), Chennai, India

    Kiran Natarajan & Mohan Kameswaran

  4. ZETA Research Ltd., Trieste, Italy

    Simonetta Ballali

  5. MERF Institute of Speech & Hearing (MERF-ISH), Chennai, India

    Ranjith Rajeswaran

  6. Department of Pediatrics, Maulana Azad Medical College, New Delhi, India

    Gulshan Sethi

Authors
  1. Ileana Baldi
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  2. Achal Gulati
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  3. Giulia Lorenzoni
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  4. Kiran Natarajan
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  8. Dario Gregori
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  9. Gulshan Sethi
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Correspondence to Ileana Baldi.

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Baldi, I., Gulati, A., Lorenzoni, G. et al. Public Health Implications of Obstructive Sleep Apnea Burden. Indian J Pediatr 81 (Suppl 1), 55–62 (2014). https://doi.org/10.1007/s12098-014-1539-8

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  • DOI: https://doi.org/10.1007/s12098-014-1539-8

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