Abstract
A newborn presented with erythematous lesion over face, which appeared soon after birth. Diagnosis of neonatal lupus erythematosus (NLE) was confirmed by positive anti-Ro SSA antibody and skin biopsy. But anti-La SSB antibody was negative. Her hepatic transaminases were high. But no cardiac manifestations were noted.
Similar content being viewed by others
References
Lela A. Lee, Neonatal Lupus Erythematosus: Clinical Findings and Pathogenesis. J Invest Dermatol 2004; 9: 52–56.
Yukiko N. Immune responses to SS-A 52-kDa and 60-kDa proteins and to SS-B 50-kDa protein in mothers of infants with neonatal lupus erythematosus, B J Dermatol 2000; 142: 908–912.
Sawant Shankar, Amladi ST, Wadhawa SL, Nayak CS, Nikam BP. Cutaneous neonatal lupus erythematosus with unusual features. Indian J Dermatol Venerol Leprol 2007; 4: 250–52.
Nieman AR, Lee LA, Weston WL, Buyon JP. Cutaneous manifestations of neonatal lupus without heart block: characteristics of mothers and children enrolled in a national registry. J Pediatr 2000; 137: 674–80.
Boh EE. Neonatal Lupus Erythematosus. Clin Dermatol 2004; 22: 125–128.
Jenkins RE, Kurwa AR, Atherton DJ, Black MM. Neonatal lupus erythematosus. Clin and Exp Dermatol 1994; 19: 409–411.
Taylor-Albert, E. Reichlin, M. Toews, WH. Overholt, ED, Lee, LA. Delayed dilated cardiomyopathy as a manifestation of neonatal lupus: case reports, autoanitbody analysis, and management. Pediatrics 1997; 99:733–735.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Sarkar, M., Ghosh, J.K., Sinha, M.K. et al. Anti-La negative cutaneous lupus erythematosus in a newborn. Indian J Pediatr 76, 649–650 (2009). https://doi.org/10.1007/s12098-009-0161-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-009-0161-7