Abstract
Introduction
Radiotherapy is a basic weapon in the local treatment of multiple solid tumors. The radiotherapy activity has been evaluated in our centre during the past eleven years. The study focused on rectal cancer.
Materials and methods
This is a descriptive study of all radiotherapy procedures performed between January 1998 and December 2008. It quantifies the workload of each pathology treated, the rate of irradiation and its adequacy with optimal rates of irradiation according to the best available scientific evidence.
Results
We quantified 9,622 external radiotherapy procedures of which 6,009 were associated with the five pathologies that involved the highest workloads. Of these, 905 were performed in rectal cancer. The workloads due to cancers of the breast, prostate, lung, gynaecological pathologies and rectal cancers were 23.2%, 11.8%, 11.6%, 6.3% and 9.3% respectively. The real “radiotherapy utilisation rates” of these pathologies were 62%, 20.2%, 34.3%, 21% and 64% respectively, while the “rates of adequacy” were 74.7%, 33.6%, 45.1%, 60% and 104.8%.
Conclusions
The “radiotherapy utilisation rate” for rectal cancer was equivalent to the estimated optimum rate as defined on the basis of reference groups. The therapy utilised developed chronologically in parallel with the available scientific evidence. The radiotherapy utilisation rates for breast and prostate cancer gradually increased, with a tendency to reach optimal rates. Radiotherapy as a treatment for lung cancer was underutilised. In global terms, the rate of utilisation of radiation therapy was low, although it displayed a tendency to increase.
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References
(1990) NIH consensus conference. Adjuvant therapy for patients with colon and rectal cancer. JAMA 264:1444–1450
(1997) Improved survival with preoperative radiotherapy in resectable rectal cancer. Swedish Rectal Cancer Trial. N Engl J Med 336:980–987
Cammà C, Giunta M, Fiorica F et al (2000) Preoperative radiotherapy for resectable rectal cancer: a meta-analysis. JAMA 284:1008–1015
Kapiteijn E, Marijnen CA, Nagtegaal ID et al; Dutch Colorectal Cancer Group (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345:638–646
Sauer R, Fietkau R, Wittekind C et al; German Rectal Cancer Group (2003), Adjuvant vs. neoadjuvant radiochemotherapy for locally advanced rectal cancer: the German trial CAO/ARO/AIO-94. Colorectal Dis 5:406–415
Cervantes A, Roselló S, Rodríguez-Braun E et al (2008) Progress in the multidisciplinary treatment of gastrointestinal cancer and the impact on clinical practice: perioperative management of rectal cancer. Ann Oncol 19[Suppl 7]:vii266–272
(1984) Clasificación internacional de Enfermedades, 9th Revision MC, 2nd edn. Madrid: Ministerio de Sanidad y Consumo
Ferlay J, Bray F, Pisani P, Parkin DM (2004) GLOBOCAN 2002: Cancer Incidence, Mortality and Prevalence Worldwide. IARC Cancer-Base No 5, version 2.0. Lyon, France: IARC Press
(2005) La situación del cáncer en España. Madrid: Ministerio de Sanidad y Consumo
Delaney G, Jacob S, Featherstone C, Barton M (2005) The role of radiotherapy in cancer treatment. Cancer 104:1129–1137
Delaney GP, Jacob S, Featherstone C, Barton MB (2003) Radiotherapy in cancer care: estimating optimal utilisation from a review of evidencebased clinical guidelines. Collaboration for Cancer Outcomes Research and Evaluation (CCORE). Sydney: Liverpool Hospital
Palacios Eito A, Espinosa Calvo M, Mañas Rueda A, de Las Heras M (2008) Radiation oncology: future needs and equipment. Current situation in Spain. Clin Transl Oncol 10:478–485
Fisher B, Bryant J, Wolmark N et al (1998) Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol 16:2672–2685
(1988) Consensus statements: the management of clinically localized prostate cancer. National Institutes of Health Consensus Development Panel. NCI Monogr (7):3–6. http://www.ncbi.nlm.nih.gov/pubmed/3050539
Amdur RJ, Parsons JT, Fitzgerald LT, Million RR (1990) The effect of overall treatment time on local control in patients with adenocarcinoma of the prostate treated with radiation therapy. Int J Radiat Oncol Biol Phys 19: 1377–1382
Kapiteijn E, Kranenbarg EK, Steup WH et al (1999) Total mesorectal excision (TME) with or without preoperative radiotherapy in the treatment of primary rectal cancer. Prospective randomised trial with standard operative and histopathological techniques. Dutch ColoRectal Cancer Group. Eur J Surg 165:410–420
Sauer R, Becker H, Hohenberger W et al; German Rectal Cancer Study Group (2004) Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351:1731–1740
Pahlman L, Glimelius B (1990) Pre- or postoperative radiotherapy in rectal and rectosigmoid carcinoma. Report from a randomized multicenter trial. Ann Surg 211:187–195
Viñes JJ, Ardanaz E, Arrazola A, Gaminde I (2003) Population-based epidemiology of colorectal cancer: causality review. An Sist Sanit Navar 26:79–97
van Daal WA, Bos MA (1997) Infrastructure for radiotherapy in The Netherlands: development from 1970 to 2010. Int J Radiat Oncol Biol Phys 37:411–415
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García Cabezas, S., Palacios Eito, A., Martínez Paredes, M. et al. Radiotherapy in rectal cancer: development, adequacy and radiotherapy utilisation rate. A comparative analysis with the most frequent tumour sites. Clin Transl Oncol 13, 115–120 (2011). https://doi.org/10.1007/s12094-011-0628-7
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DOI: https://doi.org/10.1007/s12094-011-0628-7