Abstract
The primary function of nasal packs is to modulate the bleeding, prevent adhesions and obstruction, with least discomfort to the subjects without risking secondary infection. However, both packing and removal of the pack is an unpleasant experience, with the latter being extremely painful. Therefore the need of the hour is a dressing which prioritizes subject comfort without compromising other desired nasal pack properties. Twenty subjects were enrolled in this interventional, open label study. The subjects had 10 hospital visits, starting from baseline (Visit 1) to postoperative day 28 (Visit 10), at regular intervals. The proportion of the population with postoperative pain alleviation and bleeding control failure (within 10 min) were the main objectives. Within 10 min of VELNEZ administration, all 20 participants got their bleeding under control. With VELNEZ, the painful nasal pack removal method was totally avoided because it was biodegradable. No moderate/severe pain, infection and adhesions were reported in any of the subjects, but few subjects reported moderate obstruction until Visit 3 (Discharge Day). In the present study, for participants undergoing nasal surgery, VELNEZ proved to be a secure and reliable nasal pack.
Trial Registration: CTRI/2021/09/036437, prospectively registered.
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There is no conflict of interest for Dr Akhil Pratap Singh, Dr Saloni Singh, Dr Ridhima Malik and Dr Ritu Gupta. Dr Siddharth Pandey is the Head of Research and Development and Vice-President at Datt mediproducts, the manufacturer of VELNEZ nasal pack. VELNEZ is the product under study in this research.
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Singh, A.P., Singh, S., Malik, R. et al. An Analysis of the VELNEZ Nasal Pack’s Acceptability and Safety for Use During Nasal Surgery: A Prospective Study. Indian J Otolaryngol Head Neck Surg 76, 1886–1890 (2024). https://doi.org/10.1007/s12070-023-04437-2
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DOI: https://doi.org/10.1007/s12070-023-04437-2