Abstract
Solitary extramedullary plasmacytoma (SEP) of the nasal cavity is a rare neoplastic condition characterized by the localized proliferation of abnormal plasma cells. We present a case of SEP involving the nasal cavity in a 40-year-old male patient who presented with nasal obstruction and recurrent epistaxis. The diagnosis was confirmed through clinical evaluation, imaging studies, and histopathological examination of excised specimen. The patient underwent trans-nasal endoscopic excision of nasal mass without any adjuvant therapy, which resulted in successful local control. This case report highlights the clinical presentation, diagnostic approach, treatment modalities, and favourable prognosis associated with solitary extramedullary plasmacytoma of the nasal cavity.
Similar content being viewed by others
References
Belić B, Mitrović S, Arsenijević S, Erdevicki L, Stojanović J, Stojanović S, Stolić R (2013) Feb;70(2):221-4 Nasal septum extramedullary plasmacytoma. Vojnosanit Pregl. doi: https://doi.org/10.2298/vsp1302221b. PMID: 23607192
Shreif JA, Goumas PD, Mastronikolis N, Naxakis SS (2001) Jan;124(1):119 – 20 Extramedullary plasmacytoma of the nasal cavity. Otolaryngol Head Neck Surg. doi: https://doi.org/10.1067/mhn.2001.112480. PMID: 11228468
Corvo MA, Granato L, Ikeda F, de Próspero JD (2013 Apr) Extramedullary nasal plasmacytoma: literature review and a rare case report. Int Arch Otorhinolaryngol 17(2):213–217. https://doi.org/10.7162/S1809-97772013000200016PMID: 25992016; PMCID: PMC4423260
Uppal HS, Harrison P (2001) Sep;115(9):745-6 Extramedullary plasmacytoma of the larynx presenting with upper airway obstruction in a patient with long-standing IgD myeloma. J Laryngol Otol. doi: https://doi.org/10.1258/0022215011908829. PMID: 11564308
Hu H, Hu X, Hu G, Li D, Cai J (2023) Diagnosis and management of extramedullary plasmacytoma in nasal cavity: Clinical experience and literature review. Medicine (Baltimore). Jan 13;102(2):e32647. doi: https://doi.org/10.1097/MD.0000000000032647. PMID: 36637932; PMCID: PMC9839280
Wax MK, Yun KJ, Omar RA (1993) Nov;109(5):877 – 85 Extramedullary plasmacytomas of the head and neck. Otolaryngol Head Neck Surg. doi: https://doi.org/10.1177/019459989310900517. PMID: 8247569
Majumdar S, Raghavan U, Jones NS (2002) Nov;116(11):962-5 Solitary plasmacytoma and extramedullary plasmacytoma of the paranasal sinuses and soft palate. J Laryngol Otol. doi: https://doi.org/10.1258/00222150260369561. PMID: 12487681
Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, Samson D, Guidelines Working Group of the UK Myeloma Forum (2004) Mar;124(6):717 – 26 ; ; British Committee for Standards in Haematology; British Society for Haematology. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol. doi: https://doi.org/10.1111/j.1365-2141.2004.04834.x. PMID: 15009059
Sabattini E, Bacci F, Sagramoso C, Pileri SA (2010 Jun) WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview. Pathologica 102(3):83–87 PMID: 21171509
Funding
None.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Disclaimer
Authors declare that the views expressed in this report are their own.
Disclosure of Potential Conflicts of Interest
The authors declare that they have no conflict of interest.
Research Involving Human Participants and/or Animals
Not applicable.
Informed Consent
Written Informed consent has been obtained from patient.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Mishra, U.P., Verma, A.K. & Chaurasia, J.K. Solitary Extramedullary Plasmacytoma of Nasal Cavity. Indian J Otolaryngol Head Neck Surg 75, 4060–4065 (2023). https://doi.org/10.1007/s12070-023-04061-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12070-023-04061-0