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Catalytic dearomative hydroboration of heteroaromatic compounds

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Abstract

This review offers a comprehensive discussion on literature concerning the development of catalytic protocols for the dearomative hydroboration of heteroaromatic compounds. The importance of selective dearomatization of heteroarenes, their remarkable applications along with the development of different catalytic methods and their synthetic scopes are emphasized.

Graphic abstract

The dearomatization/aromatization process of pyridine motif enables dihydropyridine (DHP) derivatives to act as a key intermediate in deriving biologically active species, pharmaceuticals, organocatalyst and sophisticated reducing agents. This review offers a complete overview of recent development of catalytic protocols for the dearomative hydroboration of heteroaromatic compounds.

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Acknowledgement

CG thanks SERB New Delhi (EMR/2016/002517), DAE and NISER for financial support.

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  1. Basujit Chatterjee

    Present address: Max Planck Institute for Chemical Energy Conversion, Stiftstraße 34-36, 45470, Mülheim an der Ruhr, Germany

Authors and Affiliations

  1. School of Chemical Sciences, National Institute of Science Education and Research, HBNI, Bhubaneswar, 752 050, Odisha, India

    Basujit Chatterjee & Chidambaram Gunanathan

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  1. Basujit Chatterjee
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Correspondence to Chidambaram Gunanathan.

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Special Issue on 150 years of the Periodic Table

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Chatterjee, B., Gunanathan, C. Catalytic dearomative hydroboration of heteroaromatic compounds. J Chem Sci 131, 118 (2019). https://doi.org/10.1007/s12039-019-1710-x

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  • DOI: https://doi.org/10.1007/s12039-019-1710-x

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