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Hybrid Low-Grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma of the Pancreas

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References

  1. Chew W, Benson C, Thway K, Hayes A, Miah A, Zaidi S, et al. Clinical characteristics and efficacy of chemotherapy in sclerosing epithelioid fibrosarcoma. Med Oncol. 2018;35(11):138–44. https://doi.org/10.1007/s12032-018-1192-6.

  2. Evans HL. Low-grade fibromyxoid sarcoma. (1987) A report of two metastasizing neoplasms having a deceptively benign appearance. Am J Clin Pathol 88(5):615–619. https://doi.org/10.1093/ajcp/88.5.615.

  3. Fletcher C, Bridge J, Hogendoorn P, et al. (2013) World Health Organization classification of tumours of soft tissue and bone: pathology and genetics of tumours of soft tissue and bone, 4th ed. Lyon, France: IARC Press.

  4. Meis-Kindblom JM, Kindblom LG, Enzinger FM. Sclerosing epithelioid fibrosarcoma: a variant of fibrosarcoma simulating carcinoma. Am J Surg Pathol. 1995;19(9):979–93. https://doi.org/10.1097/00000478-199509000-00001.

  5. Prieto-Granada C, Zhang L, Chen HW, Sung YS, Agaram NP, Jungbluth AA, et al. A genetic dichotomy between pure sclerosing epithelioid fibrosarcoma (SEF) and hybrid SEF/low-grade fibromyxoid sarcoma: a pathologic and molecular study of 18 cases. Genes Chromosomes Cancer. 2015;54(1):28–38. https://doi.org/10.1002/gcc.22215.

  6. Maretty-Nielsen K, Baerentzen S, Keller J, et al. (2013) Low-grade fibromyxoid sarcoma: incidence, treatment strategy of metastases, and clinical significance of the FUS gene. 2013:1-6. https://doi.org/10.1155/2013/256280.

  7. Colovic R, Grubor N, Misev M, et al. Fibromyxoid sarcoma of the pancreas. Srp Arh Celok Lek. 2008;136(3):158–61. https://doi.org/10.2298/SARH0804158C.

  8. Fujii S, Kawawa Y, Horiguchi S, Kamata N, Kinoshita T, Ogawa T. Low-grade fibromyxoid sarcoma of the small bowel mesentery: computed tomography and magnetic resonance imaging findings. Radiat Med. 2008;26(4):244–7. https://doi.org/10.1007/s11604-007-0214-7.

  9. Kim KJ, Seo JW. Intra-abdominal low-grade fibromyxoid sarcoma of the transverse mesocolon mimicking lymphoma. Jpn J Radiol. 2014;32(6):360–4. https://doi.org/10.1007/s11604-014-0305-1.

  10. Mendoza AS, O’Leary MP, Peng SK, et al. Low-grade fibromyxoid sarcoma of the sigmoid colon. Exp Mol Pathol. 2015;98(2):300–3. https://doi.org/10.1016/j.yexmp.2015.02.007.

  11. Park IJ, Kim HC, Yu CS, Kim JS, Jang SJ, Kim JC. Low-grade fibromyxoid sarcoma of the colon. Dig Liver Dis. 2007;39(3):274–7. https://doi.org/10.1016/j.dld.2006.01.015.

  12. Winfield HL, de las Casas L, Greenfield W, et al. Low-grade fibromyxoid sarcoma presenting clinically as a primary ovarian neoplasm: a case report. Int J Gynecol Pathol. 2007;26(2):173–6. https://doi.org/10.1097/01.pgp.0000228145.36807.43.

  13. Bai S, Jhala N, Adsay NV, Wei S. Sclerosing epithelioid fibrosarcoma of the pancreas. Ann Diagn Pathol. 2013;17(2):214–6. https://doi.org/10.1016/j.anndiagpath.2011.06.006.

  14. Carvalho EA, Bonomi DO, Pinho AJM, Salles PGO, Vieira HC. Primary sclerosing epithelioid fibrosarcoma of the pleura. J Bras Pneumol. 2017;43(6):490–1 https://doi.org/10.1590/s1806-37562017000000198.

    Article  Google Scholar 

  15. Ertoy Baydar D, Kosemehmetoglu K, Aydin O, Bridge JA, Buyukeren B, Aki FT. Primary sclerosing epithelioid fibrosarcoma of kidney with variant histomorphologic features: report of 2 cases and review of the literature. Diagn Pathol. 2015;10:186 https://doi.org/10.1186/s13000-015-0420-z.

    Article  Google Scholar 

  16. Frattini JC, Sosa JA, Carmack S, Robert ME. Sclerosing epithelioid fibrosarcoma of the cecum: a radiation-associated tumor in a previously unreported site. Arch Pathol Lab Med. 2007;131(12):1825–8. https://dx.doi.org/. https://doi.org/10.1043/1543-2165.

  17. Evans HL. Low-grade fibromyxoid sarcoma: a clinicopathologic study of 33 cases with long-term follow-up. Am J Surg Pathol. 2011;35(10):1450–62. https://doi.org/10.1046/j.1365-2559.1998.00530.x.

  18. Baheti AD, Tirumani SH, Rosenthal MH, Howard SA, Shinagare AB, Ramaiya NH, et al. Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. Am J Roentgenol. 2015;204(2):374–85. https://doi.org/10.2214/AJR.14.12888.

  19. Hwang S, Kelliher E, and Hameed M. (2012) Imaging features of low-grade fibromyxoid sarcoma (Evans tumor). 41(10):1263-72. https://doi.org/10.1007/s00256-012-1417-2.

  20. Torriani M, Etchebehere M, Amstalden EM, Ouellette H. Magnetic resonance imaging of low-grade fibromyxoid sarcoma. Clinics. 2006;61(3):267–70 https://doi.org/10.1590/S1807-59322006000300012.

    Article  Google Scholar 

  21. Eyden BP, Manson C, Banerjee SS, Roberts IS, Harris M. Sclerosing epithelioid fibrosarcoma: a study of five cases emphasizing diagnostic criteria. Histopathology. 1998;33(4):354–60. https://doi.org/j.1365-2559.1998.00530.x.

  22. Christensen D, Ramsamooj R, Gilbert TJ. Sclerosing epithelioid fiberosarcoma: short T2 on MR imaging. Skelet Radiol. 1997;26(10):619–21. https://doi.org/10.1007/s002560050297.

  23. Yue Y, Liu Y, Song L, Chen X, Wang Y, Wang Z. MRI findings of low-grade fibromyxoid sarcoma: a case report and literature review. BMC Musculoskelet Disord. 2018;19(1):65. https://doi.org/10.1186/s12891-018-1976-z.

  24. Sargar K, Kao SC, Spunt SL, Hawkins DS, Parham DM, Coffin C, et al. MR and CT imaging of low-grade fibromyxoid sarcoma in children: a report from the children’s oncology group study ARST0332. Am J Roentgenol. 2015;205(2):414–20. https://doi.org/10.2214/AJR.14.13972.

  25. Luo Y, Hu W, Wu H, Xue H, Huo L, Li F, et al. 18F-fluorodeoxyglucose PET/CT features and correlations with histopathologic characteristics in sclerosing epithelioid fibrosarcoma. Int J Clin Exp Pathol. 2014;7(10):7278–85.

  26. Arbajian E, Puls F, Magnusson L, et al. F. (2014). Recurrent EWSR1-CREB3L1 gene fusions in sclerosing epithelioid fibrosarcoma. Am J Surg Pathol 38(6):801–808. https://doi.org/10.1097/PAS.0000000000000158.

  27. Mok Y, Pang YH, Sanjeev JS, Kuick CH, Chang KT. Primary renal hybrid low-grade fibromyxoid sarcoma-sclerosing epithelioid fibrosarcoma: an unusual pediatric case with EWSR1-CREB3L1 fusion. Pediatr Dev Pathol. 2018;21(6):574–9. https://doi.org/10.1177/1093526617754030.

  28. Doyle LA, Wang WL, Dal Cin P, et al. MUC4 is a sensitive and extremely useful marker for sclerosing epithelioid fibrosarcoma. Am J Surg Pathol. 2012;36(10):1444–51. https://doi.org/10.1097/PAS.0b013e3182562bf8.

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Authors and Affiliations

  1. Department of Radiology and Biomedical Imaging, UCSF Medical Center, 505 Parnassus Ave, San Francisco, CA, 94143, USA

    Sage P Kramer MD, Zhen J Wang MD & Spencer C Behr MD

  2. Department of Pathology, UCSF Medical Center, San Francisco, CA, USA

    Christopher J Bowman MD PhD, Kathleen M Sheahon MD, Soo-Jin Cho MD PhD & Sarah E Umetsu MD PhD

  3. Division of General Surgery, UCSF Medical Center, CA, San Francisco, USA

    Eric K Nakakura MD PhD

Authors
  1. Sage P Kramer MD
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  2. Christopher J Bowman MD PhD
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  6. Soo-Jin Cho MD PhD
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Correspondence to Spencer C Behr MD.

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Kramer, S.P., Bowman, C.J., Wang, Z.J. et al. Hybrid Low-Grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma of the Pancreas. J Gastrointest Canc 51, 1025–1029 (2020). https://doi.org/10.1007/s12029-020-00369-0

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