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Incidence of Colorectal Cancer and Adenomatous Polyps After a Two-Step Screening in Isfahan Province, Iran in 2018

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Abstract

Purpose

The aim of this study was to estimate the incidence of colorectal cancers in Iran. The results of this study are based on a screening program that is being implemented in Isfahan province.

Material and Methods

In this study, about 137,000 people were screened for colorectal cancer and adenomatous polyps in 2 steps during the year 2018.

Results

Based on the findings of this study, the incidence of adenomatous polyps was reported to be 389 (95% CI, 365–422) per 100,000 population. The incidence of adenomatous polyps was reported to be 483 (95% CI, 446–520) and 316 (95% CI, 286–346) in men and women, respectively (p < 0.001). Also, the incidence of colorectal cancer was reported to be 33 (95% CI, 23–42) per 100,000 population. The incidence of colorectal cancer in men and women was reported to be 41 (95% CI, 30–51) and 26 (95% CI, 17–34), respectively, indicating a statistically non-significant difference (p = 0.29).

Conclusion

Based on the result of this study, despite a low participation rate of the target population in the screening program, the incidence of adenomatous polyps and colorectal cancer is relatively high in the average-risk population.

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Acknowledgments

The authors would like to thank all personnel of Isfahan Health Centers. We also would like to thank in particular Ms. Zahra Ravankhah who is responsible for Cancer Registry in Isfahan for providing data.

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Correspondence to Seyyed Mohammad Tabatabaei.

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Soodejani, M.T., Mirzaei, H., Manesh, M.M. et al. Incidence of Colorectal Cancer and Adenomatous Polyps After a Two-Step Screening in Isfahan Province, Iran in 2018. J Gastrointest Canc 51, 850–854 (2020). https://doi.org/10.1007/s12029-019-00313-x

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