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Status of Colorectal Cancer Devices: Present Scenario

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Journal of Gastrointestinal Cancer Aims and scope Submit manuscript

Abstract

Purpose

The purpose of this study was the colonoscopic detection and removal of neoplasia from the colorectum to prevent the development of colorectal cancer.

Method

Various online medical databases were searched such as PubMed, ACS, NCI, NIH, WHO, etc. for relevant publications and clinical trials for new developments in colonoscopic devices that are intended for diagnostic visualization and therapeutic interventions of the digestive tract.

Result

HD colon and I-Scan both has shown to increase the detection of sporadic adenomas with high quality. Third Eye Retroscope confers the backward view of colon, but aeroscope screens the entire colon in 30–60 min. Narrow-band imaging enhances mucosal and vascular details through the color differentiation of precancerous or cancerous polyp, compared to white light colonoscopy. The PillCam Colon Capsule is another new technique which is easily inserted and painless. In case of chemotherapy, Therasphere with Yttrium-90 has good results in the treatment of colorectal adenocarcinoma metastasis. Radiofrequency ablation is a good technique for tumors ablation and Staple Line Reinforcement prevents the leak during and post-surgery of colon. FOBT is much more sensitive and cheaper test for colorectal cancer screening.

Conclusion

Registered clinical trials have shown promising results for neoplasia detection by I-Scan, TER, and NBI imaging techniques will change current colonoscopic practice in colorectal cancer screening. However, more studies and inventions are required for improving the patient safety and efficacy.

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Abbreviations

ACS:

American Cancer Society

AGA:

American Gastroenterological Association

ASGE:

American Society of Gastrointestinal Endoscopy

CARP:

Compression anastomotic ring-locking procedure

CRC:

Colorectal cancer

CTC:

Computed tomography colonography

DEBIRI:

Drug-eluting bead irinotecan

FIT:

Fecal immunochemical testing

FOBT:

Fecal occulted blood test

HD:

High definition

MRI:

Magnetic resonance imaging

NBI:

Narrow-band imaging

NIH:

National Institutes of Health

NCI:

National Cancer Institute

OC:

Optical colonoscopy

PET:

Positron emission tomography

RFA:

Radiofrequency ablation

SLR:

Staple line reinforcement

TER:

Third Eye Retroscope

TRE:

Transparent retractable extension

WHO:

World Health Organization

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Acknowledgments

This work was not supported by any grant and funding agency.

Conflict of Interest

The authors have no conflicts of interest to declare.

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Authors and Affiliations

  1. Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India

    Shammy Chandel, Reyhan Akhtar, Pooja Sarotra & Bikash Medhi

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  1. Shammy Chandel
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  2. Reyhan Akhtar
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Correspondence to Bikash Medhi.

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Chandel, S., Akhtar, R., Sarotra, P. et al. Status of Colorectal Cancer Devices: Present Scenario. J Gastrointest Canc 46, 91–103 (2015). https://doi.org/10.1007/s12029-015-9686-3

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