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Endoscopic Submucosal Dissection Combined with the Placement of Biodegradable Stents for Recurrent Esophageal Cancer After Chemoradiotherapy

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Abstract

We report a case of a patient with esophageal squamous cell carcinoma who presented with obstruction of the esophagus. On endoscopy, a central ulcerating lesion was found spreading to the anterior wall of the middle esophagus. Four courses of chemoradiation therapy successfully produced a complete response for 3 years. A recurrence occurred which consisted of a morphologically flat lesion that occupied the entire circumference of the esophagus. Endoscopic submucosal dissection removed all lesions en bloc. To prevent a post-procedure mucosal defect of the circumference of the esophagus, biodegradable poly-l-lactic acid monofilaments esophageal stents were placed on the same day. One month later, the patient reported a feeling of obstruction. An endoscopic examination revealed food stuck in the stents, this was removed, and balloon dilatation provided good passage which has been maintained for 7 months.

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Authors and Affiliations

  1. Division of Digestive Endoscopy, Department of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu, 520-2192, Japan

    Yosuke Mochizuki & Yasuharu Saito

  2. Division of Mucosal Immunology, Graduate School of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu, Japan

    Akira Andoh

  3. Department of Radiology, Shiga University of Medical Science, Seta-Tukinowa, Otsu, Japan

    Toyohiko Tanaka, Norihisa Nitta & Kiyoshi Murata

  4. Department of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu, Japan

    Tomoyuki Tsujikawa & Yoshihide Fujiyama

  5. Kyoto Medical Planning Co. Ltd, Yamashina, Kyoto, Japan

    Hirokazu Yamada

Authors
  1. Yosuke Mochizuki
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  2. Yasuharu Saito
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  3. Toyohiko Tanaka
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  4. Norihisa Nitta
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  5. Hirokazu Yamada
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  6. Tomoyuki Tsujikawa
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  7. Kiyoshi Murata
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  8. Yoshihide Fujiyama
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  9. Akira Andoh
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Corresponding author

Correspondence to Yasuharu Saito.

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Mochizuki, Y., Saito, Y., Tanaka, T. et al. Endoscopic Submucosal Dissection Combined with the Placement of Biodegradable Stents for Recurrent Esophageal Cancer After Chemoradiotherapy. J Gastrointest Canc 43, 324–328 (2012). https://doi.org/10.1007/s12029-011-9283-z

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  • DOI: https://doi.org/10.1007/s12029-011-9283-z

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