Skip to main content

Advertisement

Log in

Uterine Leiomyosarcoma Metastasis to the Pancreas: Report of a Case and Review of the Literature

  • Brief Communication
  • Published:
Journal of Gastrointestinal Cancer Aims and scope Submit manuscript

Abstract

Introduction

Uterine leiomyosarcoma is an aggressive malignant tumor that often leads to metastatic dissemination, generally in the lungs, liver, brain, and bones. Despite the fact that pancreatic neoplasms spread easily, the pancreas is not a usual target organ from other neoplasms.

Case Report

We present a rare case of metastasis to the pancreas from uterine leiomyosarcoma treated with segmental resection with no recurrence at this stage. A review of the literature is later presented showing no similar case to what has been reported.

Discussion

Surgical resection of unique pancreatic metastases is a safe practice. An increase in the survival rate has been demonstrated after resection of metastases from renal cell carcinoma, although it has not been proved with metastases from other locations. Further trials are needed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Leath 3rd CA, Huh WK, Straughn Jr JM, Conner MG. Uterine leiomyosarcoma metastatic to the thyroid. Obstet Gynecol. 2002;100(5 Pt 2):1122–4.

    Article  PubMed  Google Scholar 

  2. Ma L, Wu S, Zou Y, Li W, Gong L, Gerelle G, et al. One-stage surgery of low-grade malignant intravenous uterine leiomyosarcomatosis with right atrium extension. Ann Thorac Surg. 2007;84(2):644–7.

    Article  PubMed  Google Scholar 

  3. Moreno-Cabral RJ, Fukuyama O, Powell WS, Gold S, McNamara JJ. Surgical resection of giant metastatic leiomyosarcoma of the heart. J Thorac Cardiovasc Surg. 1987;94(3):447–9.

    PubMed  CAS  Google Scholar 

  4. Saiz AD, Sachdev U, Brodman ML, Deligdisch L. Metastatic uterine leiomyosarcoma presenting as a primary sarcoma of the parotid gland. Obstet Gynecol. 1998;92(4 Pt 2):667–8.

    Article  PubMed  CAS  Google Scholar 

  5. Kaziro GS. Metastatic uterine leiomyosarcoma to the tongue: report of case. J Oral Surg. 1981;39(2):128–9.

    PubMed  CAS  Google Scholar 

  6. Aarvold A, Bann S, Giblin V, Wotherspoon A, Mudan SS. Osteosarcoma metastasising to the duodenum and pancreas. J Bone Joint Surg Br. 2007;89(4):542–4.

    Article  PubMed  CAS  Google Scholar 

  7. Eloubeidi MA, Jhala D, Chhieng DC, Jhala N, Eltoum I, Wilcox CM. Multiple late asymptomatic pancreatic metastases from renal cell carcinoma: diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy with immunocytochemical correlation. Dig Dis Sci. 2002;47(8):1839–42.

    Article  PubMed  Google Scholar 

  8. Noseda A, Gangji D, Cremer M. Acute pancreatitis as presenting symptom and sole manifestation of small cell lung carcinoma. Dig Dis Sci. 1987;32(3):327–31.

    Article  PubMed  CAS  Google Scholar 

  9. Yeung KY, Haidak DJ, Brown JA, Anderson D. Metastasis-induced acute pancreatitis in small cell bronchogenic carcinoma. Arch Intern Med. 1979;139(5):552–4.

    Article  PubMed  CAS  Google Scholar 

  10. Niccolini DG, Graham JH, Banks PA. Tumor-induced acute pancreatitis. Gastroenterology. 1976;71(1):142–5.

    PubMed  CAS  Google Scholar 

  11. David AW, Samuel R, Eapen A, Vyas F, Joseph P, Sitaram V. Pancreatic metastasis from renal cell carcinoma years after nephrectomy: a case report and review of the literature. Trop Gastroenterol. 2006;27(4):175–6.

    PubMed  Google Scholar 

  12. Sohn TA, Yeo CJ, Cameron JL, Nakeeb A, Lillemoe KD. Renal cell carcinoma metastatic to the pancreas: results of surgical management. J Gastrointest Surg. 2001;5(4):346–51.

    Article  PubMed  CAS  Google Scholar 

  13. Reddy S, Edil BH, Cameron JL, Pawlik TM, Herman JM, Gilson MM, et al. Pancreatic resection of isolated metastases from nonpancreatic primary cancers. Ann Surg Oncol. 2008;15(11):3199–206.

    Article  PubMed  Google Scholar 

  14. Sperti C, Pasquali C, Liessi G, Pinciroli L, Decet G, Pedrazzoli S. Pancreatic resection for metastatic tumors to the pancreas. J Surg Oncol. 2003;83(3):161–6.

    Article  PubMed  Google Scholar 

  15. Stankard CE, Karl RC. The treatment of isolated pancreatic metastases from renal cell carcinoma: a surgical review. Am J Gastroenterol. 1992;87(11):1658–60.

    PubMed  CAS  Google Scholar 

  16. Bachmann J, Michalski CW, Bergmann F, Büchler MW, Kleeff J, Friess H. Metastasis of rectal adenocarcinoma to the pancreas. Two case reports and a review of the literature. JOP. 2007;8(2):214–22.

    PubMed  Google Scholar 

  17. Hiotis SP, Klimstra DS, Conlon KC, Brennan MF. Results after pancreatic resection for metastatic lesions. Ann Surg Oncol. 2002;9:675–9.

    Article  PubMed  Google Scholar 

  18. Z'graggen K, Fernandez-del Castillo C, Rattner DW, Sigala H, Warshaw AL. Metastases to the pancreas and their surgical extirpation. Arch Surg. 1998;133:413–7.

    Article  PubMed  Google Scholar 

  19. Birkmeyer JD, Siewers AE, Finlayson EV, Stukel TA, Lucas FL, Batista I, et al. Hospital volume and surgical mortality in the United States. N Engl J Med. 2002;346:1128–37.

    Article  PubMed  Google Scholar 

  20. Büchler MW, Wagner M, Schmied BM, Uhl W, Friess H, Z’graggen K. Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. Arch Surg. 2003;138:1310–4.

    Article  PubMed  Google Scholar 

  21. Wente MN, Kleeff J, Esposito I, Hartel M, Müller MW, Fröhlich BE, et al. Renal cancer cell metastasis into the pancreas: a single-center experience and overview of the literature. Pancreas. 2005;30:3.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jaime Alonso Gómez.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Alonso Gómez, J., Arjona Sánchez, Á., Martínez Cecilia, D. et al. Uterine Leiomyosarcoma Metastasis to the Pancreas: Report of a Case and Review of the Literature. J Gastrointest Canc 43, 361–363 (2012). https://doi.org/10.1007/s12029-010-9172-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12029-010-9172-x

Keywords

Navigation