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Sustained fever resolved promptly after total thyroidectomy due to huge Hashimoto’s fibrous thyroiditis

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Abstract

We encountered a 55-year-old female patient with Hashimoto’s thyroiditis who showed persistent fever, and could not find any source of fever other than the large nontender goiter. Her fever continued with positive CRP for 6 months. Although we did not assume that the inflammation was related to Hashimoto’s thyroiditis, total thyroidectomy was performed for cosmetic reasons; however, fever was resolved immediately after thyroidectomy. Pathological diagnosis was Hashimoto’s chronic thyroiditis. Immunohistochemical staining showed that the follicular cells were positive for IL-1alpha, IL-1beta, and TNF-alpha. We believed that fever was induced by inflammatory cytokines produced in thyroid. The case indicated that Hashimoto’s thyroiditis with nontender goiter could cause idiopathic fever.

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References

  1. R.S. Zimmerman, M.D. Brennan, W.M. McConahey, J.R. Goellner, H. Gharib, Ann. Intern. Med. 104, 355–357 (1986)

    PubMed  CAS  Google Scholar 

  2. T. Ishihara, T. Mori, N. Waseda, K. Ikekubo, T. Akamizu, H. Imura, Endocrinol. Jpn.. 33, 701–712 (1986)

    PubMed  CAS  Google Scholar 

  3. C. Shigemasa, Y. Ueta, Y. Mitani, S. Taniguchi, K. Urabe, T. Tanaka, A. Yoshida, H. Mashiba, J. Clin. Endocrinol. Metab. 70, 385–390 (1990)

    Article  PubMed  CAS  Google Scholar 

  4. T. Ishihara, T. Mori, N. Waseda, K. Ikekubo, H. Kurahachi, H. Imura, Endocrinol. Jpn. 35, 231–236 (1988)

    PubMed  CAS  Google Scholar 

  5. Y.C. Kon, L.J. DeGroot, J. Clin. Endocrinol. Metab. 88, 2667–2672 (2003)

    Article  PubMed  CAS  Google Scholar 

  6. H. Ohye, S. Fukata, S. Kubota, I. Sasaki, Y. Takamura, F. Matsuzuka, N. Amino, K. Kuma, A. Miyauchi, K. Kakudo, Thyroid 15, 340–345 (2005)

    Article  PubMed  Google Scholar 

  7. Y. Bando, K. Notumata, T. Toya, N. Tanaka, M. Fugisawa, Endocr. J. 44, 603–609 (1997)

    PubMed  CAS  Google Scholar 

  8. C.A. Dinarello, J. Endotoxin Res. 10, 201–222 (2004)

    PubMed  CAS  Google Scholar 

  9. T. Ishihara, T. Mori, N. Waseda, K. Ikekubo, T. Akamizu, H. Imura, Endocrinol. Jpn. 34, 831–841 (1987)

    PubMed  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. kuma Hospital, 8-2-35 Shimoyamate-Dori, Chuo-Ku, Kobe, 650-0011, Japan

    Sumihisa Kubota, Fumio Matsuzuka, Hidemi Ohye, Eijun Nishihara, Takumi Kudo, Mitsuru Ito, Takeshi Arishima, Shuji Fukata, Mitsuyoshi Hirokawa, Nobuyuki Amino & Akira Miyauchi

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  1. Sumihisa Kubota
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  2. Fumio Matsuzuka
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  3. Hidemi Ohye
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  4. Eijun Nishihara
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  5. Takumi Kudo
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  6. Mitsuru Ito
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  7. Takeshi Arishima
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  8. Shuji Fukata
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  9. Mitsuyoshi Hirokawa
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  10. Nobuyuki Amino
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  11. Akira Miyauchi
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Correspondence to Sumihisa Kubota.

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Kubota, S., Matsuzuka, F., Ohye, H. et al. Sustained fever resolved promptly after total thyroidectomy due to huge Hashimoto’s fibrous thyroiditis. Endocr 31, 88–91 (2007). https://doi.org/10.1007/s12020-007-0013-z

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  • DOI: https://doi.org/10.1007/s12020-007-0013-z

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