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Clinical Analysis of Brain Trauma-Associated SIADH

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Abstract

The objective of this study was to analyze the clinical features of brain trauma associated syndrome of inappropriate antidiuretic hormone secretion. A retrospective analysis was performed for the electrolytes and osmolality of blood and urine samples of brain injury patients, which have been collected in our department since last 20 years. Four cases of brain injury patients met the criteria of SIADH, and three of them were cured but one patient died. In conclusion, the pathogenesis and treatment of SIADH associated with brain injury are different from hyponatremia. Early diagnosis and treatment can reduce the morbidity and mortality of patients with traumatic brain injury.

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Acknowledgments

The authors thank Ms. Hong Tang and Ms. Wei Sun for their assistance in data collection.

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Authors and Affiliations

  1. Department of Neurosurgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, 10#, Changjiang Branch, Daping, Yuzhong District, Chongqing, 400042, People’s Republic of China

    Lizhao Chen, Minhui Xu, Yongwen Zou & Lunshan Xu

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  1. Lizhao Chen
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  2. Minhui Xu
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  3. Yongwen Zou
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  4. Lunshan Xu
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Corresponding author

Correspondence to Lunshan Xu.

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Contribution of Authors

Lizhao Chen, Minhui Xu, Yongwen Zou, and Lunshan Xu collected the study cases and performed SIADH diagnosis. Lizhao Chen was responsible for writing the paper under the direction of Lunshan Xu.

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Chen, L., Xu, M., Zou, Y. et al. Clinical Analysis of Brain Trauma-Associated SIADH. Cell Biochem Biophys 69, 703–706 (2014). https://doi.org/10.1007/s12013-014-9856-0

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  • DOI: https://doi.org/10.1007/s12013-014-9856-0

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