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Moderately High Dose Zinc Gluconate or Zinc Glycinate: Effects on Plasma Zinc and Erythrocyte Superoxide Dismutase Activities in Young Adult Women

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Abstract

Some zinc (Zn) research studies have used either Zn gluconate or Zn glycinate, but the two forms have not been compared much. Therefore, a moderately high dose of the two forms (60 mg Zn/day) were compared in a 6-week intervention in young adult women. Plasma Zn, the traditional assessment of Zn status, was increased in all subjects given Zn glycinate (N = 10), while no significant change was seen overall for Zn gluconate or placebo (N = 10 each). Erythrocyte superoxide dismutase activity, a marker for Zn-induced copper deficiency, was unchanged in all three groups. Thus, for the conditions of this study, Zn glycinate effectively changed Zn status better than Zn gluconate, but neither impacted copper status.

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Conflict of Interest

R. DiSilvestro is currently using zinc glycinate in products affiliated with his startup company, but that was not the case at the time the study was done (which was over 12 years ago).

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  1. Human Nutrition, Ohio State University, 345 Campbell Hall, 1787 Neil Ave, Columbus, OH, 43210, USA

    Robert A. DiSilvestro, Erin Koch & Linda Rakes

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  1. Robert A. DiSilvestro
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  2. Erin Koch
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  3. Linda Rakes
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Correspondence to Robert A. DiSilvestro.

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DiSilvestro, R.A., Koch, E. & Rakes, L. Moderately High Dose Zinc Gluconate or Zinc Glycinate: Effects on Plasma Zinc and Erythrocyte Superoxide Dismutase Activities in Young Adult Women. Biol Trace Elem Res 168, 11–14 (2015). https://doi.org/10.1007/s12011-015-0334-3

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  • DOI: https://doi.org/10.1007/s12011-015-0334-3

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