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Synthesis of 2-Ethylhexyl Palmitate Catalyzed by Enzyme Under Microwave

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Abstract

2-Ethylhexyl palmitate has been prepared in organic solvents catalyzed by an immobilized lipase QLM. Microwave irradiation was used to improve the enzyme activity and shorten the reaction time. The reaction conditions under microwave have been optimized. Compared with that of the free QLM under classical heating, the immobilized QLM under microwave exhibited higher enzyme activity and the conversion could achieve 99% in about 3.0 h. Furthermore, the immobilized QLM displayed excellent reusability under microwave irradiation.

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Acknowledgements

We are gratefully for the financial support from the Fund of Basic Scientific Research from Jilin University (for Constructing the Scientific and Technological Platform, 2017) and the Foundation of Changchun BC&HC Pharmaceutical Technology Co., Ltd. (No. 3R116V401465).

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  1. Lei Wang and Yang Zhang contributed equally to this work.

Authors and Affiliations

  1. Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University, No. 2699 Qianjin Street, Changchun, 130023, China

    Lei Wang, Yuxin Zhang, Lu Zheng, He Huang & Zhi Wang

  2. Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, 130022, People’s Republic of China

    Yang Zhang

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  1. Lei Wang
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Correspondence to Zhi Wang.

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Wang, L., Zhang, Y., Zhang, Y. et al. Synthesis of 2-Ethylhexyl Palmitate Catalyzed by Enzyme Under Microwave. Appl Biochem Biotechnol 185, 347–356 (2018). https://doi.org/10.1007/s12010-017-2666-2

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