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Lessons learned from the International Renal Cell Carcinoma-Venous Thrombus Consortium (IRCC-VTC)

  • Kidney Diseases (G Ciancio, Section Editor)
  • Published:
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Abstract

Renal cell carcinoma (RCC) extension into the renal vein or the inferior vena cava occurs in 4 %–10 % of all kidney cancer cases. This entity shows a wide range of different clinical and surgical scenarios, making natural history and oncological outcomes variable and poorly characterized. Infrequency and variability make it necessary to share the experience from different institutions to properly analyze surgical outcomes in this setting. The International Renal Cell Carcinoma–Venous Tumor Thrombus Consortium was created to answer the questions generated by competing results from different retrospective studies in RCC with venous extension on current controversial topics. The aim of this article is to summarize the experience gained from the analysis of the world's largest cohort of patients in this unique setting to date.

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Abbreviations

RCC:

renal cell carcinoma

IRCCVTC:

international renal cell carcinoma-venous thrombus consortium

IVC:

inferior vena cava

CPB:

cardiopulmonary bypass

RAE:

renal artery embolization

(AJCC):

American Joint Committee on Cancer

(UICC):

Union International Contre le Cancer

SSIGN:

Stage, Size, Grade, Necrosis score

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Conflict of Interest

Dr. Juan I. Martínez-Salamanca, Dr. Estefania Linares, Dr. Javier González, Dr. Roberto Bertini, Dr. Joaquín A. Carballido, Dr. Thomas Chromecki, Dr. Sia Daneshmand, Dr. Christopher P. Evans, Dr. Paolo Gontero, Dr. Axel Haferkamp, Dr. Markus Hohenfellner, Dr. William C. Huang, Dr. Theresa M. Koppie, Dr. Viraj A. Master, Dr. Rayan Matloob, Dr. James M. McKiernan, Dr. Carrie M. Mlynarczyk, Dr. Francesco Montorsi, Dr. Hao G. Nguyen, Dr. Giacomo Novara, Dr. Sascha Pahernik, Dr. Juan Palou, Dr. Raj S. Pruthi, Dr. Krishna Ramaswamy, Dr. Oscar Rodriguez Faba, Dr. Paul Russo, Dr. Shahrokh F. Shariat, Dr. Martin Spahn, Dr. Carlo Terrone, Dr. Derya Tilki, Dr. Daniel Vergho, Dr. Eric M. Wallen, Dr. Evanguelos Xylinas, Dr. Richard Zigeuner, and Dr. John A. Libertino each declare no potential conflicts of interest relevant to this article.

Dr. Gaetano Ciancio is a section editor for Current Urology Reports.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Correspondence to Juan I. Martínez-Salamanca.

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Martínez-Salamanca, J.I., Linares, E., González, J. et al. Lessons learned from the International Renal Cell Carcinoma-Venous Thrombus Consortium (IRCC-VTC). Curr Urol Rep 15, 404 (2014). https://doi.org/10.1007/s11934-014-0404-7

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