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Hypertension Across a Woman’s Life Cycle

  • Hypertension and the Heart (B Upadhya, Section Editor)
  • Published:
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Abstract

Purpose of Review

We reviewed the effects of hypertension and the means to prevent and treat it across the spectrum of a woman’s lifespan and identified gaps in sex-specific mechanisms contributing to hypertension in women that need to be addressed.

Recent Findings

Hypertension continues to be an important public health problem for women across all life stages from adolescence through pregnancy, menopause, and older age. There remain racial, ethnic, and socioeconomic differences in hypertension rates not only overall but also between the sexes. Blood pressure cutoffs during pregnancy have not been updated to reflect the 2017 ACC/AHA changes due to a lack of data. Additionally, the mechanisms behind hypertension development in menopause, including sex hormones and genetic factors, are not well understood.

Summary

In the setting of increasing inactivity and obesity, along with an aging population, hypertension rates are increasing in women. Screening and management of hypertension throughout a women’s lifespan are necessary to reduce the burden of cardiovascular disease, and further research to understand sex-specific hypertension mechanisms is needed.

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Correspondence to Bharathi Upadhya.

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Lama Ghazi receives grant funding from American Heart Association Postdoctoral Fellowship award (829804). Natalie A. Bello receives grant funding from the NIH/NHLBI (K23-HL136853, R01-HL153382) and is a member of a CEC for a GSK trial. Bharathi Upadhya reported receiving honoraria from Novartis. Rahul V. Annabathula, Li Zhou, and Richard Brandon Stacey declare that they have no conflict of interest.

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Ghazi, L., Annabathula, R.V., Bello, N.A. et al. Hypertension Across a Woman’s Life Cycle. Curr Hypertens Rep 24, 723–733 (2022). https://doi.org/10.1007/s11906-022-01230-4

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