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Effect of Egg Consumption on Blood Pressure: a Systematic Review and Meta-analysis of Randomized Clinical Trials

  • Nutrition and Hypertension (T Mori, Section Editor)
  • Published:
Current Hypertension Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

We identified and quantified the results of randomized controlled trials (RCTs) that have assessed the impact of egg consumption on blood pressure in adults.

Recent Findings

We conducted a comprehensive search of medical bibliographic databases up to February 2019 for RCTs investigating the effect of egg consumption on blood pressure in adults. Fifteen RCTs were included with a total of 748 participants. Overall, egg consumption had no significant effect on systolic blood pressure (weighted mean difference (WMD) = 0.046 mmHg; 95% CI − 0.792, 0.884) and diastolic blood pressure (WMD = − 0.603 mmHg; 95% CI − 1.521, 0.315). Subgroup analyses had no effect on pooled results and no heterogeneity was found among included studies.

Summary

Egg consumption has no significant effects on systolic and diastolic blood pressure in adults. Due to several limitations among existing studies, general conclusions cannot be drawn regarding the beneficial or neutral impact of egg consumption on blood pressure in adults.

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Abbreviations

CVD:

Cardiovascular diseases

HTN:

Hypertension

CHD:

Coronary heart disease

RR:

Relative risk

RCTs:

Randomized controlled trials

SBP:

Systolic blood pressure

DBP:

Diastolic blood pressure

PRISMA:

Preferred reporting items for systematic review and meta-analyses

PROSPERO:

Prospective register of systematic reviews

WMD:

Weighted mean differences

CAD:

Coronary artery disease

IHD:

Ischemic heart disease

IQW:

Ile-Gln-Trp

LKP:

Leu-Lys-Pro

IRW:

Ile-Arg-Trp

NO:

Nitric oxide

ACE:

Angiotensin converting enzyme

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Acknowledgments

We thank Iran University of Medical Sciences for providing facilities to search in electronic databases.

Availability of Data and Material

It was registered in the PROSPERO (international prospective register of systematic reviews) database under the number CRD42019127500.

Funding

ZSC is currently supported by NIH T32 DK007135-44.

Author information

Authors and Affiliations

  1. Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran

    Roya Kolahdouz-Mohammadi & Masoumeh Khalighi Sikaroudi

  2. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

    Mahsa Malekahmadi & Naseh Pahlavani

  3. Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA

    Zachary Stephen Clayton

  4. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran

    Seyede Zahra Sadat

  5. Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Sepideh Soltani

Authors
  1. Roya Kolahdouz-Mohammadi
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  3. Zachary Stephen Clayton
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Contributions

RKM screened and selected the trials, extracted the data, and wrote the manuscript. MM screened and selected the trials, extracted the data, and assessed quality of included studies. ZSC reviewed and edited the manuscript. SZS screened the trials. NP screened and selected the trials and assessed quality of included studies. MKS screened the trials. SS conceived the idea, conducted the research, analyzed the data, and performed statistical analysis and had primary responsibility for final content. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Sepideh Soltani.

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Kolahdouz-Mohammadi, R., Malekahmadi, M., Clayton, Z.S. et al. Effect of Egg Consumption on Blood Pressure: a Systematic Review and Meta-analysis of Randomized Clinical Trials. Curr Hypertens Rep 22, 24 (2020). https://doi.org/10.1007/s11906-020-1029-5

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  • DOI: https://doi.org/10.1007/s11906-020-1029-5

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