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Hypertension and adrenal disorders

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Abstract

Adrenal disorders causing hypertension can be related to the dysfunction of either the adrenal cortex or the adrenal medulla. These disorders, including congenital adrenal hyperplasia (CAH), owing to 11β-hydroxylase deficiency and to 17α-hydroxylase deficiency; apparent mineralocorticoid excess; familial hyperaldosteronism type I; primary aldosteronism; Cushing’s syndrome; and familial glucocorticoid resistance, primarily affect the adrenal cortex and cause low-renin hypertension. The classic disorder of the adrenal medulla resulting in hypertension is pheochromocytoma, although hypertension in obesity might also be associated with catecholamine secretion. In this review, we discuss these etiologies and the most recent advances in our knowledge of their pathophysiology, diagnosis, and treatment.

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Authors and Affiliations

  1. The New York Presbyterian Hospital, Weill Medical College of Cornell University, Pediatric Endocrinology, Room M-630, 525 East 68th Street, Box 103, 10021, New York, NY, USA

    Wassim Chemaitilly MD, Robert C. Wilson PhD & Maria I. New MD

Authors
  1. Wassim Chemaitilly MD
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  2. Robert C. Wilson PhD
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  3. Maria I. New MD
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Chemaitilly, W., Wilson, R.C. & New, M.I. Hypertension and adrenal disorders. Current Science Inc 5, 498–504 (2003). https://doi.org/10.1007/s11906-003-0058-1

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  • DOI: https://doi.org/10.1007/s11906-003-0058-1

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