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Radiation-Associated Valvular Disease

  • Valvular Heart Disease (TL Kiefer, Section Editor)
  • Published:
Current Cardiology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Radiation-associated valvular disease (RAVD) is characterized by late valvular manifestations following radiation exposure to the mediastinum. Review of current guidelines was performed to examine best practices to reduce risk and optimize outcomes in this patient population.

Recent Findings

Early and consistent screening and comprehensive and careful planning are critical in managing RAVD. Due to long latency periods, serial screening and targeted evaluation of risk factors are essential to early detection. Varying and complex presentations of RAVD require an integrated team of experienced specialists equipped with multimodality imaging-based screening protocols to stratify risk, plan intervention, and evaluate treatment response.

Summary

Patients with valvular manifestations associated with radiation therapy call for an individualized plan of care involving longitudinal multimodality imaging-based screening and experienced decision-making regarding timing and strategy of intervention to improve patient outcomes.

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Authors and Affiliations

  1. Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA

    Samantha Xu, Eoin Donnellan & Milind Y. Desai

  2. Department of Cardiovascular Imaging, Cleveland Clinic, Cleveland, OH, USA

    Milind Y. Desai

Authors
  1. Samantha Xu
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  2. Eoin Donnellan
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  3. Milind Y. Desai
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Correspondence to Milind Y. Desai.

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This article is part of the Topical Collection on Valvular Heart Disease

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Xu, S., Donnellan, E. & Desai, M.Y. Radiation-Associated Valvular Disease. Curr Cardiol Rep 22, 167 (2020). https://doi.org/10.1007/s11886-020-01411-0

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  • DOI: https://doi.org/10.1007/s11886-020-01411-0

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