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Postoperative survival after lumbar instrumented surgery for metastatic spinal tumors: a nationwide population-based cohort analysis

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Abstract

Background

It is difficult to predict the expected survival after lumbar instrumented surgery for metastases owing to the difference among different cancer origins and the relatively short survival after surgery.

Aims

The aim of this study is to analyze the postoperative survival period of lumbar spinal metastasis patients who underwent lumbar instrumented surgery.

Methods

Data were collected from the Korean National Health Insurance Review and Assessment Service database. Patients who underwent lumbar spinal surgery with instrumentation between January 2011 and December 2015 for metastatic lumbar diseases were reviewed. The mean postoperative survival period of patients with metastatic lumbar cancer according to each primary cancer type was evaluated.

Results

A total of 628 patients were enrolled and categorized according to primary cancer type. The overall median survival rate was 1.11±1.30 years. The three most prevalent primary cancer groups were lung, hepatobiliary, and colorectal cancers, presenting relatively short postoperative survival rates (0.93±1.25, 0.74±0.75 and 0.74±0.88 years, respectively). The best postoperative survival period was observed in breast cancer (2.23±1.83 years), while urinary tract cancer showed the shortest postoperative survival period (0.59±0.69 years).

Conclusion

The postoperative survival period of patients with lumbar metastatic spinal tumors according to different primary cancers after instrumented fusion was ˃1 year overall, with differences according to different primary origins. This result may provide information regarding the expected postoperative survival after instrumented surgery for lumbar spinal metastases.

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Data availability

The data that support the findings of this study are available from the corresponding author, [WKK], upon reasonable request, in the form allowed by the HIRA.

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Acknowledgements

We would like to express our gratitude to Professor Geum Jun Cho and his team for their valuable support during the data analysis process.

Funding

This study was supported by the grant funded by the National Research Foundation of Korea grant funded by the Korean Ministry of Education (2021R1I1A1A01042679) and partially by the Korea University College of Medicine grant (K2107421, O2000981).

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Authors and Affiliations

  1. Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, 148 Gurodong-ro, Guro-gu, Seoul, 08308, Republic of Korea

    Seung Hoon Lee, Woo-Keun Kwon, Chang Hwa Ham, Jung Hyun Na & Joo Han Kim

  2. Department of Neurosurgery, Gachon University Gil Medical Center, Incheon, Republic of Korea

    Youn-Kwan Park

  3. Department of Neurosurgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea

    Jung Yul Park & Junseok W Hur

  4. Department of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO, USA

    Hong Joo Moon

Authors
  1. Seung Hoon Lee
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  2. Woo-Keun Kwon
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  3. Chang Hwa Ham
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  4. Jung Hyun Na
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  7. Jung Yul Park
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  8. Junseok W Hur
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  9. Hong Joo Moon
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Corresponding author

Correspondence to Woo-Keun Kwon.

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Ethical approval

All human subjects study procedures were in accordance with the ethical standards of our Institutional Review Board and the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed consent

In this retrospective study, the requirement for informed consent was waived.

Conflict of interest

The authors declare no competing interests.

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Lee, S.H., Kwon, WK., Ham, C.H. et al. Postoperative survival after lumbar instrumented surgery for metastatic spinal tumors: a nationwide population-based cohort analysis. Ir J Med Sci 193, 51–56 (2024). https://doi.org/10.1007/s11845-023-03459-7

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  • DOI: https://doi.org/10.1007/s11845-023-03459-7

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