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Urgent lung transplantation in acute fibrinous and organizing pneumonia: a sliding door or a new perspective?

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Abstract

Background

Lung transplantation is nowadays the standard therapy for certain well-defined chronic end-stage lung diseases, even in patients on mechanical ventilation or extracorporeal life support. While these latter techniques have been used worldwide as bridging options to lung transplantation for listed patients, they are not commonly used in previously healthy patients developing acute not-reversible lung failure.

Methods

We will discuss two patients without any relevant medical history developing acute lung failure evolving to irreversible acute fibrinous and organising pneumonia (AFOP), thus listed for urgent lung transplantation.

Results

The patients recovered well, and both are still alive.

Conclusions

In the absence of clear guidelines, our approach showed, in these patients, the possible benefits of lung transplantation regarding survival in AFOP.

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Author notes

  1. Alessio Campisi and Andrea Dell’Amore equally contributed to this paper.

Authors and Affiliations

  1. Department of CardioThoracic Surgery, S. Orsola Malpighi Hospital, Via Massarenti 9, Bologna, Italy

    Alessio Campisi, Andrea Dell’Amore, Luca Bertolaccini, Stefano Congiu, Giampiero Dolci & Franco Stella

  2. Department of Anaesthesiology, S. Orsola Malpighi Hospital, Bologna, Italy

    Giulia Piccone & Erika Dal Checco

Authors
  1. Alessio Campisi
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  2. Andrea Dell’Amore
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  3. Luca Bertolaccini
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  4. Stefano Congiu
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  5. Giampiero Dolci
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  6. Giulia Piccone
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  7. Erika Dal Checco
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  8. Franco Stella
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Contributions

(I) Conception and design: AC, LB, GP; (II) administrative support: AD, AC, FS; (III) provision of study materials or patients: GP, EDC, AC, GD; (IV) collection and assembly of data: AC, GP, SC; (V) data analysis and interpretation: AD, AC; (VI) manuscript writing: AC, AD, LB; (VII) final approval of manuscript: all authors. All authors discussed the results and contributed to the final manuscript.

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Correspondence to Alessio Campisi.

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Campisi, A., Dell’Amore, A., Bertolaccini, L. et al. Urgent lung transplantation in acute fibrinous and organizing pneumonia: a sliding door or a new perspective?. Gen Thorac Cardiovasc Surg 68, 136–141 (2020). https://doi.org/10.1007/s11748-019-01183-7

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  • DOI: https://doi.org/10.1007/s11748-019-01183-7

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