Abstract
Because the number of ideal brain-dead donors is limited, active use of marginal donors is currently one of the major issues discussed in regard to lung transplantation. We report a case in which the patient underwent single-lung transplantation for chronic pulmonary emphysema. The lung came from a marginal, ABO blood group nonidentical, compatible donor. Because the donor was marginal (pneumonia in the right lung and lobar atelectasis in both lungs), all recipient candidates with ABO blood group identical declined. Thus, a nonidentical, compatible recipient had a chance to receive a lung transplant. This 49-year-old man underwent single-lung transplantation for chronic pulmonary emphysema with severe respiratory failure. He had a good postoperative clinical course.
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Reyes KG, Mason DP, Thuita L, Nowicki ER, Murthy SC, Pettersson GB et al. Guidelines for donor lung selection: time for revision? Ann Thorac Surg 2010;89:1756–1764.
Sundaresan S, Semenkovich J, Ochoa L, Richardson G, Trulock EP, Cooper JD, et al. Successful outcome of lung transplantation is not compromised by the use of marginal donor lungs. J Thorac Cardiovasc Surg 1995;109:1075–1079.
Botha P, Fisher AJ, Dark JH. Marginal lung donors: a diminishing margin of safety? Transplantation 2006;82:1273–1279.
Noiseux N, Nguyen BK, Marsolais P, Dupont J, Simard L, Houde I, et al. Pulmonary recruitment protocol for organ donors: a new strategy to improve the rate of lung utilization. Transplant Proc 2009;41:3284–3289.
Lardinois D, Banysch M, Korom S, Hillinger S, Rousson V, Boehler A, et al. Extended donor lungs: eleven years experience in a consecutive series. Eur J Cardiothorac Surg 2005;27:762–767.
Thabut G, Mal H, Cerrina J, Dartevelle P, Dromer C, Velly JF, et al. Influence of donor characteristics on outcome after lung transplantation: a multicenter study. J Heart Lung Transplant 2005;24:1347–1353.
Weill D, Dey GC, Young KR, Zorn GL, Early LJ, Hicks RA, et al. A positive donor gram stain does not predict the development of pneumonia, oxygenation, or duration of mechanical ventilation following lung transplantation. J Heart Lung Transplant 2001;20:255.
McGiffin DC, Zorn GL, Young KR, Kirklin JK, Leon KJ, Wille KM, et al. The intensive care unit oxygen challenge should not be used for donor lung function decision-making. J Heart Lung Transplant 2005;24:1902–1905.
Hunt BJ, Yacoub M, Amin S, Devenish A, Contreras M. Induction of red blood cell destruction by graft-derived antibodies after minor ABO-mismatched heart and lung transplantation. Transplantation 1998;46:246–249.
Sano Y, Date H, Nagahiro I, Aoe M, Shimizu N. Relationship between anti-ABO antibody production and hemolytic anemia after minor ABO-mismatched living-donor lobar lung transplantation. Transplant Proc 2005;37:1371–1372.
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Susaki, Y., Inoue, M., Minami, M. et al. Single-lung transplantation in a chronic pulmonary emphysema patient with a marginal donor who was ABO blood group nonidentical but compatible. Gen Thorac Cardiovasc Surg 60, 312–315 (2012). https://doi.org/10.1007/s11748-011-0824-y
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DOI: https://doi.org/10.1007/s11748-011-0824-y