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Magnetic responsive scaffolds and magnetic fields in bone repair and regeneration

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Abstract

Increasing evidence shows that magnetic fields and magnetic responsive scaffolds can play unique roles in promoting bone repair and regeneration. This article addresses the synergistic effects of magnetic scaffolds in response to external magnetic fields on the bone regeneration in situ. Additionally, the exploration of using magnetic scaffolds as tools in the bone implant fixation, local drug delivery and mimicking microenvironment of stem cell differentiation are introduced. We also discussed possible underlying mechanisms and perspectives of magnetic responsive scaffolds in the bone repair and regeneration.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Institute of Basic Medical Sciences, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, 100005, China

    Hai-Yan Xu

  2. State Key Laboratory of Bioelectronics and Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science & Medical Engineering, Southeast University, Nanjing, 210096, China

    Ning Gu

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  1. Hai-Yan Xu
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  2. Ning Gu
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Correspondence to Hai-Yan Xu or Ning Gu.

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Xu, HY., Gu, N. Magnetic responsive scaffolds and magnetic fields in bone repair and regeneration. Front. Mater. Sci. 8, 20–31 (2014). https://doi.org/10.1007/s11706-014-0232-1

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  • DOI: https://doi.org/10.1007/s11706-014-0232-1

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