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A Randomized Controlled Trial Investigating the Impact of a Low-Calorie Dietary Approach to Stop Hypertension (DASH) on Anthropometric and Glycemic Measures in Patients Experiencing Weight Regain 2 Years Post Sleeve Surgery

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Abstract

Purpose

To evaluate the effect of a low-calorie dietary approach to stop hypertension (DASH) compared to a low-calorie diet on weight control, body composition and glycemic measures in post sleeve patients with weight regain.

Materials and Methods

Participants were randomly allocated to either the low-calorie DASH diet group (intervention) or the low-calorie diet group (control) for a duration of 16 weeks. Both groups had a prescribed caloric intake of 1000–1200 calories. The DASH diet group made dietary adjustments in accordance with the DASH pattern.

Results

At the end of the study, both interventions significantly reduced anthropometric and body composition parameters (P-value < 0.001), with a greater decrease observed in the low-calorie DASH diet group (P-value < 0.001). Insulin levels and homeostatic model assessment for insulin resistance (HOMA-IR) decreased significantly in both groups, but the magnitude of these changes was not statistically different between the two groups. After adjusting for confounders, a significant difference was observed in post-intervention values and changes in weight, body mass index, and fat mass and fat-free mass.

Conclusion

In summary, adhering to a calorie-restricted DASH diet for 16 weeks improved weight loss, body mass index, and fat mass reduction in post-bariatric patients who experienced weight regain 2 years after surgery, compared to a calorie-restricted control diet. However, there was no significant difference in the effect on blood glucose, insulin, and HOMA-IR between the two diets.

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Data Availability

The authors will make the raw data that supports the findings of this article available upon request.

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Acknowledgements

We would like to express our gratitude to all the participants for their dedication and time, as well as to the staff.

Funding

The study was supported by grant NO 43002700 from the National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Author information

Authors and Affiliations

  1. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Elahe Rashidbeygi, Atoosa Saidpour, Maryam Ghods & Soodeh Razeghi Jahromi

  2. Sports Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran

    Mastaneh Rajabian Tabesh

  3. Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran

    Morvarid Noormohammadi

  4. Tehran Obesity Treatment Center, Department of Surgery, Faculty of Medicine, Shahed University, Tehran, Iran

    Alireza Khalaj

Authors
  1. Elahe Rashidbeygi
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  4. Alireza Khalaj
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  5. Atoosa Saidpour
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Contributions

Conceptualization: S.R.J., A.Kh., A.S., and M.R.T.; methodology: S.R.J., A.Kh., A.S., and M.R.T; Statistical analysis: M.N.; investigation: E.R., and M.Gh.; data curation: E.R. and M.Gh.; writing—original draft preparation: S.R.J., M.N., and E.R; writing—review and editing: all authors; supervision: S.R.J.; All authors have read and agreed to the published version of the manuscript.

Corresponding author

Correspondence to Soodeh Razeghi Jahromi.

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Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran (IR.SBMU.NNFTRI.REC.1401.063) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Conflict of Interest

The authors declare no competing interests.

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Key Points

• The consumption of vegetables, dietary fiber, leguminous plants, and nuts was higher in the intervention group and the consumption of confectioneries, processed and red meats, sodium, and fat was higher in the low-caloric regimen group.

• A calorie-restricted DASH diet may improve weight loss, body mass index, and fat mass reduction in post-bariatric patients who have experienced weight regain 2 years after surgery.

• Calorie-restricted DASH diet demonstrated a considerably greater efficacy in reducing fat mass in comparison to a low-calorie diet, regardless of the presence of hypertension.

Elahe Rashidbeygi and Mastaneh Rajabian Tabesh equally collaborated to this study.

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Rashidbeygi, E., Tabesh, M.R., Noormohammadi, M. et al. A Randomized Controlled Trial Investigating the Impact of a Low-Calorie Dietary Approach to Stop Hypertension (DASH) on Anthropometric and Glycemic Measures in Patients Experiencing Weight Regain 2 Years Post Sleeve Surgery. OBES SURG 34, 892–901 (2024). https://doi.org/10.1007/s11695-024-07057-z

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