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Association Between the Parental Weight Status and the Weight Loss Outcome in Patients After Sleeve Gastrectomy

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Abstract

Purpose

Obesity is a complex multifactorial disease. Parents with obesity could have an impact on the weight loss outcome of their children following bariatric-metabolic surgery. Therefore, we aimed to investigate the association between the weight status of the parents and the weight loss outcome in patients undergoing sleeve gastrectomy (SG).

Methods

Patients undergoing SG with ≥ 3 years of follow-up between January 2016 and June 2018 were included in this study. The patients were categorized into three groups: (1) both parents did not have obesity (non-obesity parents, NOP); (2) one parent had obesity (single-parent obesity, SPO); (3) both parents had obesity (both parents’ obesity, BPO). The main parameters for this study were the patients’ preoperative and postoperative weight and the weight of the parents.

Results

A total of 218 SG patients were included in this study (NOP, n = 116; SPO, n = 64; BPO, n = 38). There was no statistically significant difference in the preoperative assessments. The main results for the NOP vs. SPO vs. BPO were as follows; parents’ body mass index (BMI) 23.6 ± 2.5 vs. 27.9 ± 5.0 vs. 30.2 ± 3.3 kg/m2, percentage of total weight loss (%TWL) 30.2 ± 9.0 vs. 30.8 ± 10.4 vs. 23.8 ± 10.9%. The %TWL for the BPO group was significantly lower than the NOP and SPO groups (p < 0.05).

Conclusion

The patient’s weight loss outcome was significantly lower when both parents had obesity. Further controlled or prospective studies are needed to determine the best means to improve weight loss outcomes in such patients.

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Author notes

  1. Jason Widjaja and Wei Wu contributed equally for this study

Authors and Affiliations

  1. Department of Gastrointestinal Surgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People’s Republic of China

    Jason Widjaja, Wei Wu, Libin Yao, Jian Hong, Yuxiao Chu & Xiaocheng Zhu

Authors
  1. Jason Widjaja
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  2. Wei Wu
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  3. Libin Yao
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  4. Jian Hong
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  5. Yuxiao Chu
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  6. Xiaocheng Zhu
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Corresponding author

Correspondence to Xiaocheng Zhu.

Ethics declarations

Ethics Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this retrospective study, additional formal consent is not required.

Consent to Participate

Informed consent was obtained from all individual participants included in the study.

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The authors declare no competing interests.

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Key Points

• The weight loss outcomes of patients undergoing bariatric-metabolic surgery are associated with their parents’ weight status.

• Having at least one parent with a healthy weight status could lead to better weight loss outcomes for bariatric patients.

• Future studies need to focus on the genetics of obesity, such as whether parents with obesity have different genetic expressions than parents with healthy weight status, furthermore, whether these genes are inherited by their children.

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Widjaja, J., Wu, W., Yao, L. et al. Association Between the Parental Weight Status and the Weight Loss Outcome in Patients After Sleeve Gastrectomy. OBES SURG 32, 868–872 (2022). https://doi.org/10.1007/s11695-021-05878-w

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  • DOI: https://doi.org/10.1007/s11695-021-05878-w

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