Abstract
Patients with digestive malignant tumor always have their immune function, especially the cellular immunity, suppressed to a certain extent. Traditional Chinese medicine (TCM) holds that Pi (脾)-Wei (胃) is the essence of postnatal life, and the genesis and development of digestive tumor are chiefly due to the insufficiency of vital-qi, which makes the body open to the invasion of evil pathogens. Starting from regulating the immune function of organisms, researchers recently obtained some therapeutic effects by applying the Chinese recipe, Sijunzi Decoction (四君子汤), in the treatment of digestive malignant tumors. In this paper, the related studies on the concerned basic theory and clinical application were reviewed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ren XF, Wu LB, Wang WM, et al. Regulation effect of Sijunzi Decoction on deficiency of Spleen-qi syndrome. Chin J Tradit Med Sci Technol 2005; 12(6): 359–360.
Zheng J, Zhu YJ, Zhou H, et al. The relationship between test index about the state of Spleen deficiency and survival period of carcinoma of stomach. J Pract Tradit Chin Med 2002; 18(8): 3–4.
Sun Y. The understand and prospect of prevention and treatment on carcinoma with integrated traditonal Chinese and Western medicine. Chin J Integr Tradit West Med 2000;20(8):563–565.
Li JB, Chen S, Li LX, et al. Effect of Si-Jun-Zi Decoction to lymphocety function of hypofunction of the Spleen rat. J Chengdu Univ Tradit Chin Med 2001; 1(24): 31–32.
Zhang M, Xia T, Zhang ZH, et al. Effects of Si-Jun-Zi Decoction on plasma in patients with TCM pixu. J Fourth Milit Med Univ 2000; 21(4): 411–413.
Ma MQ. Regulate immunologic functions of tumour patient by Jia Wei Si-Jun-Zi soup. Chin J Pract Chin Mod Med 2003; 3(16): 980–981.
Cui Q, Jin CG. Observation on chemotherapy and Sijunzi Decoction in treating carcinoma of esophagus after operation. Modern J Integr Tradit Chin West Med 2001; 10(15): 1409–1410.
Liang C, Zhang SH, Cai ZD, et al. Effects of early intestinal application of Sijunzi Decoction on immune function in post-operational patients of gastrointestinal tumor. Chin J Integr Tradit West Med 2005; 25(12): 1070–1073.
Ikeguchi M, Cai J, Yamane N, et al. Clinical significance of spontaneous apoptosis in advanced gastric adenocarcinoma. Cancer 1999; 85: 2329–2335.
Zhao GG, Yang JK, Zhao HL, et al. Apoptosis induction by Si-Jun-Zi Decoction in human gastric cancer xenografts in nude mice. Chin J Cancer 2001; 20(2): 164–167.
Chen DL, Huang T. Experimental study on anti-tumor effect of Si-Jun-Zi Decoction. Shandong J Tradit Chin Med 2004; 23(4): 28.
Chen DL, Huang T. Effect of Sijunzi Decoction on expression of bcl-2 protein and MMP-2 mRNA in tumor cell in vitro. Shandong J Tradit Chin Med 2004; 28(6): 470–473.
Shirraishi N, Inomata M, Osawa N. Early and late recurrence after gastrectomy for gastic carcinoma. Univariate and multivariate analyses. Cancer 2000; 89: 255.
Zheng J, Gu Y, Zhou J, et al. Effect on the living period, metastasis and recurrence of the advanced gastric cancer by the traditional Chinese medicine of Jianpi. Liaoning J Tradit Chin Med 2003; 30(8): 683–685.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wu, B., Xuan, Zr. Progress in research on applying Sijunzi Decoction (四君子汤) in treating digestive malignant tumor. Chin. J Integ. Med. 13, 156–159 (2007). https://doi.org/10.1007/s11655-007-0156-z
Received:
Issue Date:
DOI: https://doi.org/10.1007/s11655-007-0156-z