Dear Dr. Wang Jian and your team,


First and foremost, I would like to express my gratitude for the valuable suggestions and feedback to our research. Your insights have aided our work.


Regarding the issue you raised regarding the definition of early recurrence time for cHCC-CC, we acknowledge and understand the current lack of uniform standard. In order to address this matter, we plan to incorporate the overall survival period from follow-up data in our upcoming research to obtain a more accurate early recurrence time point. We will continue to strive to ensure that our research findings are more reliable and scientifically.


We also hope to receive further validation through multicenter and large-scale data in the future. We believe that through the validation of multicenter and large-scale data, our research findings will be more persuasive.


Once again, thank you for your support and encouragement toward our work. We remain committed to pursuing excellence and innovation in our future research endeavors. We eagerly look forward to any further guidance or suggestions you may have.


Yours Sincerely


Jin-yuan Liao