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An experience-based review of HIFU in functional interventional neuroradiology: transcranial MRgFUS thalamotomy for treatment of tremor

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Abstract

Tremor is a common and very disabling symptom in patients with essential tremor and Parkinson’s disease. In the recent years, transcranial ablation of thalamic nuclei using magnetic resonance guided high-intensity focused ultrasound has emerged as a minimally invasive treatment for tremor. The aim of this review is to discuss, in the light of our single-center experience, the technique, current applications, results, and future perspectives of this novel technology.

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Authors and Affiliations

  1. Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, via Vetoio 1, 67100, L’Aquila, Italy

    Federico Bruno, Francesco Arrigoni, Paolo Cerrone & Carlo Masciocchi

  2. Radiology Department, San Salvatore Hospital, L’Aquila, Italy

    Alessia Catalucci

  3. Neurology Unit, San Salvatore Hospital, L’Aquila, Italy

    Patrizia Sucapane & Davide Cerone

  4. Department of Neurosurgery, San Salvatore Hospital, L’Aquila, Italy

    Alessandro Ricci

  5. Neurology Unit, Department of Medicine, Health and Environment Sciences, L’Aquila, Italy

    Carmine Marini

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  1. Federico Bruno
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Correspondence to Federico Bruno.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the local institutional review board.

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Bruno, F., Catalucci, A., Arrigoni, F. et al. An experience-based review of HIFU in functional interventional neuroradiology: transcranial MRgFUS thalamotomy for treatment of tremor. Radiol med 125, 877–886 (2020). https://doi.org/10.1007/s11547-020-01186-y

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