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An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range

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  • Special Topic Aggregated-Induced Emission
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Abstract

Polyelectrolyte PTPEPyH, containing tetraphenylethene (TPE) and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.

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Authors and Affiliations

  1. School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, 100081, China

    DongYang Chen, JianBing Shi, YanMei Wu, Bin Tong & YuPing Dong

  2. School of Chemistry, Beijing Institute of Technology, Beijing, 100081, China

    JunGe Zhi

Authors
  1. DongYang Chen
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  2. JianBing Shi
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  3. YanMei Wu
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  4. Bin Tong
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  5. JunGe Zhi
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  6. YuPing Dong
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Correspondence to JianBing Shi or YuPing Dong.

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Chen, D., Shi, J., Wu, Y. et al. An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range. Sci. China Chem. 56, 1239–1246 (2013). https://doi.org/10.1007/s11426-013-4915-8

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  • DOI: https://doi.org/10.1007/s11426-013-4915-8

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