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Five condensed furanocoumarins from the root of Heracleum candicans Wall.

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Abstract

Three new spirotrifuranocoumarins, canditririns C–E (13), a new spirotetrafuranocoumarin, canditetrarin A (4), and a new tetrafuranocoumarin, canditetrarin B (5), were isolated from the roots of Heracleum candicans Wall. Their structures were established using spectral methods.

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References

  1. Zhonghuabencao Editorial Board (1999). Zhonghuabencao, vol 5. Shanghai Scientific and Technological Press, Shanghai, p 958 (in Chinese)

  2. Nath Y, Nazir BN, Handa KL (1961) Bergapten from the fruits of Heracleum candicans. Indian J Pharm 23:303–304

    CAS  Google Scholar 

  3. Sharma YH, Zaman A, Kidwai AR (1964) Examination of Heracleum candicans. I. Isolation and structure of a new furocoumarin, heraclenin. Tetrahedron 20:87–90

    Article  CAS  Google Scholar 

  4. Sharma YN, Sharma RC, Zaman Z, Kidwai AR (1964) Chemical examination of Heracleum candicans. II. Isolation and structure of a new furocoumarin, heraclenol. Naturwissenschaften 51:537

    Article  CAS  Google Scholar 

  5. Sharma YN, Zaman A, Kidwai AR, Bates RB, Thalacker VP (1966) Coumarin constituents of Heracleum candicans. III. Tetrahedron 22:3221–3225

    Article  CAS  Google Scholar 

  6. Bandopadhyay M, Seshadri TR (1970) Components of Heracleum candicans. I. Indian J Chem 8:855–856

    CAS  Google Scholar 

  7. Bandopadhyay M, Seshadri TR (1970) Components of Heracleum candicans. II. Indian J Chem 8:1146–1147

    CAS  Google Scholar 

  8. Bandopadhyay M, Malik SB, Seshadri TR (1971) Minor components of Heracleum candicans. I. Indian J Chem 9:731–732

    CAS  Google Scholar 

  9. Bandopadhyay M, Malik SB, Seshadri TR (1971) Candicanin, a novel bicoumarinyl derivative from the roots of Heracleum candicans. Tetrahedron Lett 45:4221–4222

    Article  Google Scholar 

  10. Bandopadhyay M, Malik SB, Seshadri TR (1973) Coumarins from the roots and seeds of Heracleum candicans. Indian J Chem 11:410–412

    CAS  Google Scholar 

  11. Bandopadhyay M, Malik SB, Seshadri TR (1973) Candicopimaric acid. Diterpene acid from the roots and seeds of Heracleum candicans. Indian J Chem 11:1097–1098

    CAS  Google Scholar 

  12. Sun H, Lin Z, Niu F (1984) Study of traditional Chinese drugs of Umbelliferae. VII. Chemical constituents of the roots of Heracleum candicans wall. (1). Yunnan Zhiwu Yanjiu 6:99–102

    CAS  Google Scholar 

  13. Lin Z, Gao L, Chen Y, Rao G, Pu F, Sun H (1993) Coumarins of Heracleum candicans. Yunnan Zhiwu Yanjiu 15:313-314

    Google Scholar 

  14. Bal-Tenbe S, Joshi DD, Lakdawala AD (1996) Isolation of the anti-inflammatory principle of Heracleum candicans. Indian J Chem 35B:518–519

    Google Scholar 

  15. Doi M, Nakamori T, Shibano M, Taniguchi M, Wang N-H, Baba K (2004) Candibirin A, a furanocoumarin dimmer isolated from Heracleum candicans Wall. Acta Cryst C60:o833–o835

    CAS  Google Scholar 

  16. Nakamori T, Taniguchi M, Shibano M, Wang N-H, Baba K (2008) Chemical studies on the root of Heracleum candicans Wall. J Nat Med 62:403–412

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

The authors are grateful to Mr. K. Minoura for NMR spectral recordings and to Mrs. M. Fujitake for mass spectra recordings at Osaka University of Pharmaceutical Sciences. This work was partially supported by NSFC (project 30270097), China.

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Correspondence to Masahiko Taniguchi.

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Taniguchi, M., Inoue, A., Shibano, M. et al. Five condensed furanocoumarins from the root of Heracleum candicans Wall.. J Nat Med 65, 268–274 (2011). https://doi.org/10.1007/s11418-010-0488-4

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  • DOI: https://doi.org/10.1007/s11418-010-0488-4

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