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Fipronil and its metabolites in chicken feather: residue analysis, depletion study, and application analysis of pollution sources in laying hens

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Abstract

A method based on a multi-mechanism impurity adsorption and ultra-performance liquid chromatography–tandem mass spectrometry was established to detect fipronil and four of its metabolites in chicken feathers. This method was successfully applied to the depletion study of fipronil in feathers of laying hens. Fipronil and two metabolites were found in feathers during treatment. Fipronil concentrations in feathers increased during medication and then regularly decreased during withdrawal, and they were still detected on the 14th day after withdrawal. High residue concentrations were also present in feathers on day 23 of the experimental period. Pollution sources of fipronil can be inferred on the basis of the residue ratio of fipronil metabolites from different pollution modes. Result shows that feathers were an effective matrix for residue monitoring and risk analysis of fipronil in animals and the environment.

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Funding

This project was supported by the National Natural Science Foundation of China (General Program, No. 31572443) and the China National Key R&D Program (2017YFC1600300).

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Authors and Affiliations

  1. Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, Beijing, 100081, China

    Decheng Suo, Zhandeng Song, Zhiming Xiao, Li Fan & Xia Fan

  2. Liaoning Agricultural Development Service Center, Shenyang, Liaoning, 110000, China

    Fenting Zhuang

Authors
  1. Decheng Suo
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  2. Zhandeng Song
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  3. Zhiming Xiao
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  4. Fenting Zhuang
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  5. Li Fan
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  6. Xia Fan
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Contributions

Suo Decheng: writing-original draft, writing-review and editing. Fan Xia: project administration, conceptualization, writing-review and editing. Song Zhandeng: test design and investigation. Xiao Zhiming: methodology study. Zhuang Fenting: sample collection and animal test. Fan Li: validation and supervision.

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Correspondence to Decheng Suo.

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Suo, D., Song, Z., Xiao, Z. et al. Fipronil and its metabolites in chicken feather: residue analysis, depletion study, and application analysis of pollution sources in laying hens. Environ Sci Pollut Res 30, 18499–18508 (2023). https://doi.org/10.1007/s11356-022-23527-2

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