Abstract
The excessive use of pesticides is posing major threats to humans and the environment. However, the environmental exposure and impact of pesticides in Pakistan have yet been systematically reviewed, despite the country’s leading role in pesticide use. Therefore, this study identified and then reviewed 85 peer-reviewed scientific publications on the topic. It was found that, compared to the worldwide average, Pakistan had high consumptions of pesticides, with an alarming increase of 1169% in the last two decades. The quantities of pesticides used followed an order of pyrethroids > organophosphates > organochlorines > carbamates, but organochlorines were the most problematic due to their environmental occurrence, the ability to transport across the media, and identified human and ecological toxicities. Additionally, the misuse or overuse of pesticides by farmers is prevailing due to insufficient knowledge about the risks, which leads to high risks in occupational exposure. These issues are further aggravated by the illegal use or continuous impacts of banned organochlorine pesticides. For the future, we suggested the establishment of organized monitoring, assessment, and reporting program based on environmental laws to minimize contamination and exposure to pesticides in Pakistan. Remediation of the contaminated areas to mitigate the adverse environmental-cum-health impacts are recommended in the most affected regions.
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References
Aamir M, Khan S, Nawab J, Qamar Z, Khan A (2016a) Tissue distribution of HCH and DDT congeners and human health risk associated with consumption of fish collected from Kabul River, Pakistan. Ecotoxicol Environ Saf 11(6):128–134. https://doi.org/10.1016/j.ecoenv.2015.12.005
Aamir M, Khan S, Niu L, Zhu S, Khan A (2016b) Occurrence, enantiomeric signature and ecotoxicological risk assessment of HCH isomers and DDT metabolites in the sediments of Kabul River, Pakistan. Environ Geochem Health 1–12 https://doi.org/10.1007/s10653-016-9847-8
Abbasi NA, Eulaers I, Jaspers VLB, Chaudhry MJI, Frantz A, Ambus PL, Covaci A, Malik RN (2016) Use of feathers to assess polychlorinated biphenyl and organochlorine pesticide exposure in top predatory bird species of Pakistan. Sci Total Environ 569–570:1408–1417. https://doi.org/10.1016/j.scitotenv.2016.06.224
Abhilash PC, Singh N (2009) Pesticide use and application an Indian scenario. J Hazard Mater 165:1–12. https://doi.org/10.1016/j.jhazmat.2008.10.061
Ahad K, Mohammad A, Mehboob F, Sattar A, Ahmad I (2006) Pesticide residues in Rawal Lake, Islamabad. Pakistan Bull Environ Contam Toxicol 76:463–470. https://doi.org/10.1007/s00128-006-0944-8
Ahad K, Mohammad A, Khan H, Ahmad I, Hayat Y (2010) Monitoring results for organochlorine pesticides in soil and water from selected obsolete pesticide stores in Pakistan. Environ Monit Assess 166:191–199. https://doi.org/10.1007/s10661-009-0995-5
Ahmad A, Shahid M, Khalid S, Zaffar H, Naqvi T, Pervez A, Bilal M, Ali MA, Abbas G, Nasim W (2019a) Residues of endosulfan in cotton growing area of Vehari, Pakistan: an assessment of knowledge and awareness of pesticide use and health risks. Environ Sci Pollut Res 26:20079–20091. https://doi.org/10.1007/s11356-018-3169-6
Ahmad SA, Anzar A, Tariq A, Altaf KF (2019b) A review on pesticides related health effects in agricultural workers of Sindh, Pakistan. Pure Applied Biology 8:1975–1979
Akhtar M, Mahboob S, Sultana S, Sultana T (2014a) Pesticides in the River Ravi and its tributaries between its stretches from Shahdara to Balloki Headworks, Punjab-Pakistan. Water Environ Res 86:13–19. https://doi.org/10.2175/106143013X13807328848612
Akhtar M, Mahboob S, Sultana S, Sultana T, Alghanim KA, Ahmed Z (2014b): Assessment of pesticide residues in flesh of Catla catla from Ravi River, Pakistan. Sci World J 1–8. https://doi.org/10.1155/2014/708532
AL-Zaidi AA, Baig MB, Muneer SET, Hussain SM, Aldosari FO (2019) Farmers’ level of knowledge on the usage of pesticides and their effects on health and environment in Northern Pakistan. J Anim Plant Sci 29:1501–1515
Alamdar A, Syed JH, Malik RN, Katsoyiannis A, Liu J, Li J, Zhang G, Jones KC (2014) Organochlorine pesticides in surface soils from obsolete pesticide dumping ground in Hyderabad City, Pakistan: contamination levels and their potential for air–soil exchange. Sci Total Environ 470–471:733–741. https://doi.org/10.1016/j.scitotenv.2013.09.053
Ali N, Khan S, Khan MA, Waqas M, Yao H (2019) Endocrine disrupting pesticides in soil and their health risk through ingestion of vegetables grown in Pakistan. Environ Sci Pollut Res 26:8808–8820. https://doi.org/10.1007/s11356-019-04287-y
Ali U, Bajwa A, Chaudhry MJI, Mahmood A, Syed JH, Li J, Zhang G, Jones KC, Malik RN (2016) Significance of black carbon in the sediment–water partitioning of organochlorine pesticides (OCPs) in the Indus River, Pakistan. Ecotoxicol Environ Saf 126:177–185. https://doi.org/10.1016/j.ecoenv.2015.12.024
Ali U, Syed JH, Malik RN, Katsoyiannis A, Li J, Zhang G, Jones KC (2014) Organochlorine pesticides (OCPs) in South Asian region: a review. Sci Total Environ 476:705–717. https://doi.org/10.1016/j.scitotenv.2013.12.107
Anwar T, Ahmad I, Tahir S (2006) Occupational exposure of farmers to pesticides in cotton growing areas of Sindh, Pakistan. Int J Biol Biotechnol 3:451–454
Anwar T, Ahmad I, Tahir S (2011) Determination of pesticide residues in fruits of Nawabshah district, Sindh, Pakistan. Pak J Bot 43:1133–1139
Anwar T, Ahmad I, Tahir AS (2012) Determination of pesticide residues in soil of Nawabshah District, Sindh, Pakistan. Pak J Zool 44(1):87–93
Anwar T, Ahmad I, Tahir S (2013) Reporting pesticide residues in soil of Lodhran District, Punjab, Pakistan. Int J Biol Res 1:143–147
Anwar T, Ahmad I, Tahir S (2014) Gas chromatographic analysis of pesticide residues in soil of Bahawalpur District, Punjab, Pakistan. Pak J Zool 46:231–236
Anwar T, Naseem J, Broacha RF, Tahir S, Ahmad I (2017) The risk and hazards of pesticides related to lack of awareness in dealers community. Int J Biol Biotechnol 14:461–466
Ashraf MA (2017) Persistent organic pollutants (POPs): a global issue, a global challenge. Environ Sci Pollut Res 24:4223–4227. https://doi.org/10.1007/s11356-015-5225-9
Asi MR, Hussain A, Muhmood ST (2008) Solid phase extraction of pesticide residues in water samples: DDT and its metabolites. Int J Environ Res 2:43–44. https://doi.org/10.22059/ijer.2010.174
Attaullah M, Yousuf MJ, Shaukat S, Anjum SI, Ansari MJ, Buneri ID, Tahir M, Amin M, Ahmad N, Khan SU (2018) Serum organochlorine pesticides residues and risk of cancer: a case-control study. Saudi J Biol Sci 25:1284–1290. https://doi.org/10.1016/j.sjbs.2017.10.023
Azizullah A, Khattak MNK, Richter P, Häder D-P (2011) Water pollution in Pakistan and its impact on public health: a review. Environ Int 37:479–497. https://doi.org/10.1016/j.envint.2010.10.007
Azmi MA, Naqvi SNH, Azmi MA, Aslam M (2006) Effect of pesticide residues on health and different enzyme levels in the blood of farm workers from Gadap (rural area) Karachi, Pakistan. Chemosphere 64:1739–1744. https://doi.org/10.1016/j.chemosphere.2006.01.016
Bajwa A, Ali U, Mahmood A, Chaudhry MJI, Syed JH, Li J, Zhang G, Jones KC, Malik RN (2016) Organochlorine pesticides (OCPs) in the Indus River catchment area, Pakistan: status, soileair exchange and black carbon mediated distribution. Chemosphere 152:292–300. https://doi.org/10.1016/j.chemosphere.2016.01.024
Baqar M, Sadef Y, Ahmad SR, Mahmood A, Li J, Zhang G (2018) Organochlorine pesticides across the tributaries of River Ravi, Pakistan Human health risk assessment through dermal exposure, ecological risks, source fingerprints and spatio-temporal distribution. Sci Total Environ 618:291–305. https://doi.org/10.1016/j.scitotenv.2017.10.234
Bondori A, Bagheri A, Allahyari MS, Damalas CA (2019) Pesticide waste disposal among farmers of Moghan region of Iran: current trends and determinants of behavior. Environ Monit Assess 191:1–9. https://doi.org/10.1007/s10661-018-7150-0
Dereumeaux C, Fillol C, Quenel P, Denys S (2020) Pesticide exposures for residents living close to agricultural lands: a review. Environ Int 134:1–14. https://doi.org/10.1016/j.envint.2019.105210
Ejaz S, Akram W, Lim CW, Lee JJ, Hussain I (2004) Endocrine disrupting pesticides: a leading cause of cancer among rural people in pakistan. Exp Oncol 26:98–105
Eqani SA-M-A-S, Malik RN, Mohammad A (2011) The level and distribution of selected organochlorine pesticides in sediments from River Chenab, Pakistan. Environ Geochem Health 33:33–47. https://doi.org/10.1007/s10653-010-9312-z
Eqani SA-M-A-S, Malik RN, Katsoyiannis A, Zhang G, Chakraborty P, Mohammad A, Jones KC (2012) Distribution and risk assessment of organochlorine contaminants in surface water from River Chenab, Pakistan. J Environ Monit 14:1645–1654. https://doi.org/10.1039/C2EM11012A
Faheem N, Sajjad A, Mehmood Z, Iqbal F, Mahmood Q, Munsif S, Waseem A (2015) The pesticide exposure through fruits and meat in Pakistan. Fresenius Environ Bull 24:4555–4566
Gómez D, Salvador P, Sanz J, Casanova C, Taratiel D, Casanova JL (2019) Desert locust detection using Earth observation satellite data in Mauritania. J Arid Environ 164:29–37. https://doi.org/10.1016/j.jaridenv.2019.02.005
Government of Pakistan GoP (1997) Policy and procedures for the filing, review and approval of environmental assessments. Pak-EPA, Islamabad
Gupta PK (2004) Pesticide exposure—Indian scene. Toxicology 198:83–90. https://doi.org/10.1016/j.tox.2004.01.021
Hassan AU, Tabinda AB, Abbas M, Khan AM (2014) Organochlorine and pyrethroid pesticides analysis in dairy milk samples collected from cotton growing belt of Punjab, Pakistan. Pakistan 51(2):321–325
Hayat K, Afzal M, Aqueel MA, Khan QM (2018) Determination of insecticide residues in fruits, vegetables, pollen, nectar and ground water of punjab (pakistan). J Agric Res 56:95–105
Hussain I, Naureen H, Ahmed I (2006) A preliminary study on risk analysis of pesticides to insectivorous birds inhabiting cotton based agro ecosystem of Punjab Pakistan. Pak J Zool 38:255–260
Huyen VN, Song NV, ThiThuy N, Dung LTP, Hoan LK (2020) Effects of pesticides on farmers’ health in Tu Ky district, Hai Duong province, Vietnam. Sustainable Futures 2:100026. https://doi.org/10.1016/j.sftr.2020.100026
Iram S, Ahmad I, Ahad K, Muhammad A, Anjum S (2009) Analysis of pesticides residues of Rawal and Simly Lakes. Pak J Bot 41:1981–1987
Jabbar A, Masud SZ, Parveen Z, Ali M (1993) Pesticide residues in cropland soils and shallow groundwater in Punjab Pakistan. Bull Environ Contam Toxicol 51:268–273. https://doi.org/10.1007/BF00198891
Jan MR, Shah J, Khawaja MA, Gul K (2009) DDT residue in soil and water in and around abandoned DDT manufacturing factory. Environ Monit Assess 155:31–38. https://doi.org/10.1007/s10661-008-0415-2
Javeres MNL, Habib R, Laure NJ, Shah STA, Valis M, Kuca K, Nurulain SM (2021) Chronic Exposure to organophosphates pesticides and risk of metabolic disorder in cohort from Pakistan and Cameroon. Int J Environ Res Public Health 18:2310. https://doi.org/10.3390/ijerph18052310
Johnson JB (2020) An overview of near-infrared spectroscopy (NIRS) for the detection of insect pests in stored grains. J Stored Prod Res 86:1–10. https://doi.org/10.1016/j.jspr.2019.101558
Khan M, Damalas CA (2015) Farmers knowledge about common pests and pesticide safety inconventional cotton production in Pakistan. Crop Prot 77:45–51. https://doi.org/10.1016/j.cropro.2015.07.014
Khan M, Mahmood HZ, Damalas CA (2015) Pesticide use and risk perceptions among farmers in the cotton belt of Punjab, Pakistan. Crop Prot 67:184–190. https://doi.org/10.1016/j.cropro.2014.10.013
Khan MI, Shoukat MA, Cheema SA, Arif HN, Niazi NK, Azam M, Bashir S, Ashraf I, Qadri R (2020) Use, contamination and exposure of pesticides in Pakistan: a review. Pak J Agric Sci 57:131–149. https://doi.org/10.21162/PAKJAS/20.7437
Khan MS, Shah MM, Mahmood Q, Hassan A, Akbar AK (2011) Assessment of pesticide residues on selected vegetables of Pakistan. J Chem Soc Pak 33:816–821
Khurshid M, Nafees M, Khan A, Yin H, Ullah W, Rashid W, Han H, Lashari AH (2022) Off-season agriculture encroachment in the uplands of Northern Pakistan: need for sustainable land management. Land 11:520–534. https://doi.org/10.3390/land11040520
Kori RK, Thakur RS, Kumar R, Yadav RS (2018) Assessment of adverse health effects among chronic pesticide-exposed farm workers in Sagar District of Madhya Pradesh, India. Int J Nutr Pharmacol Neurol Dis 8:153–161. https://doi.org/10.4103/ijnpnd.ijnpnd_48_18
Krawinkel MB, Plehn G, Kruse H, Kasi AM (1989) Organochlorine residues in Baluchistan Pakistan blood and fat concentrations in humans. Bull Environ Contam Toxicoly 43:821–826. https://doi.org/10.1007/BF01702050
Latif Y, Sherazi STH, Bhanger MI (2011) Assessment of pesticide residues in commonly used vegetables in Hyderabad, Pakistan. Ecotoxicol Environ Saf 74:2299–2303. https://doi.org/10.1016/j.ecoenv.2011.07.030
Li Z (2018) The use of a disability adjusted life year DALY metric to measure human health damage resulting from pesticide maximum legal exposures. Sci Total Environ 639:438–456. https://doi.org/10.1016/j.scitotenv.2018.05.148
Loha KM, Lamoree M, Weiss JM, Boer J (2018) Import, disposal, and health impacts of pesticides in the East Africa Rift(EAR) zone: a review on management and policy analysis. Crop Prot 112:322–331. https://doi.org/10.1016/j.cropro.2018.06.014
Mahboob S, Niazi F, AlGhanim K, Sultana S, Al-Misned F, Ahmed Z (2015) Health risks associated with pesticide residues in water, sediments and the muscle tissues of Catla catla at Head Balloki on the River Ravi. Environ Monit Assess 187:1–10. https://doi.org/10.1007/s10661-015-4285-0
Mahmood A, Malik RN, Li J, Zhang G (2014a) Human health risk assessment and dietary intake of organochlorine pesticides through air, soil and food crops (wheat and rice) along two tributaries of river Chenab, Pakistan. Food Chem Toxicol 71:17–25. https://doi.org/10.1016/j.fct.2014.05.008
Mahmood A, Malik RN, Li J, Zhang G (2014b) Levels, distribution pattern and ecological risk assessment of organochlorines pesticides (OCPs) in water and sediments from two tributaries of the Chenab River, Pakistan. Ecotoxicology 23:1713–1721. https://doi.org/10.1007/s10646-014-1332-5
Malik RN, Mehboob F, Ali U, Katsoyiannis A, Schuster JK, Moeckel C, Jones KC (2014) Organo-halogenated contaminants (OHCs) in the sediments from the Soan River, Pakistan: OHCs(adsorbed TOC) burial flux, status and risk assessment. Sci Total Environ 481:343–351. https://doi.org/10.1016/j.scitotenv.2014.02.042
Meftaul IM, Venkateswarlu K, Dharmarajan R, Annamalai P, Megharaj M (2020) Pesticides in the urban environment: a potential threat that knocks at the door. Sci Total Environ 711:1–53. https://doi.org/10.1016/j.scitotenv.2019.134612
Mehmood A, Mahmood A, Eqani SAMAS, Ishtiaq M, Ashraf A, Bibi N, Qadir A, Li J, Zhang G (2016) A review on emerging persistent organic pollutants: current scenario in Pakistan. Hum Ecol Risk Assess 23:1–13. https://doi.org/10.1080/10807039.2015.1133241
Mehmood Y, Arshad M, Kaechele H, Mahmood N, Kong R (2020) Pesticide residues, health risks, and vegetable farmers’ risk perceptions in Punjab, Pakistan. Hum Ecol Risk Assess Int J 27:846–864. https://doi.org/10.1080/10807039.2020.1776591
Moher D, Tetzlaff J, Tricco AC, Sampson M, Altman DG (2007) Epidemiology and reporting characteristics of systematic reviews. PLoS Med 4(3):e78. https://doi.org/10.1371/journal.pmed.0040078
Mubushar M, Aldosari FO, Baig MB, Alotaibi BM, Khan AQ (2019a) Assessment of farmers on their knowledge regarding pesticide usage and biosafety. Saudi J Biol Sci 26:1903–1910. https://doi.org/10.1016/j.sjbs.2019.03.001
Mubushar M, Aldosari FO, Baig MB, Alotaibi BM, Khan AQ (2019b): Assessment of farmers on their knowledge regarding pesticide usage and biosafety. Saudi J Biol Sci 26https://doi.org/10.1016/j.sjbs.2019.03.001
Mubushar M, Aldosari FO, Baig MB, Alotaibi BM, Khan AQ (2019c) Assessment of farmers on their knowledge regarding pesticide usage and biosafety. Saudi J Biol Sci 26:1903–1910. https://doi.org/10.1016/j.sjbs.2019.03.001
Mumtaz M, Qadir A, Mahmood A, Mehmood A, Malik RN, Li J, Yousaf Z, Jamil N, Shaikh IA, Ali H, Zhang G (2015) Human health risk assesment, congener specific analysis and spatial distribution pattern of organochlorine pesticides (OCPs) through rice crop from selected districts of punjab province, pakistan. Sci Total Environ 511:354–361. https://doi.org/10.1016/j.scitotenv.2014.12.030
Munshi AB, Detlef S-B, Schneider R, Zuberi R (2004) Organochlorine concentrations in various fish from different locations at Karachi Coast. Mar Pollut Bull 49:597–601. https://doi.org/10.1016/j.marpolbul.2004.03.019
Neelab, Asi MR, Kali S, Riaz MA, Waseem A, Iqbal MM, Ahmad N, Iqbal M, Masood N, Zafar MI (2020): Comparative efficacy of mitigation techniques for the detoxification of Prunus persica (L.) from selected pesticide residues. Environ Sci Pollut Res 1–9 https://doi.org/10.1007/s11356-020-08720-5
Oaks JL, Gilbert M, Virani MZ, Watson RT, Meteyer CU, Rideout BA, Shivaprasad HL, Ahmed S, Chaudhry MJI, Arshad M, Mahmood S, Ali A, Khan AA (2004) Diclofenac residues as the cause of vulture population decline in Pakistan. Nature 427:630–634. https://doi.org/10.1038/nature02317
Popp J, Pető K, Nagy J (2013) Pesticide productivity and food security. A Review. Agron Sustain Dev 33:243–255. https://doi.org/10.1007/s13593-012-0105-x
Pretty J (2018) Intensification for redesigned and sustainable agricultural systems. Science 362:1–9. https://doi.org/10.1126/science.aav0294
Quraishi R, Akbar F, Karim S, Neelab AS, Rashid W, Ullah S (2015) Effects of pesticides on haematology, thyroid stimulating hormone (TSH) and tri-iodothyronine (T3) hormones of agricultural workers in Swat, Pakistan. J Biol Life Sci 6:96–107. https://doi.org/10.5296/jbls.v6i1.6463
Rafique N, Tariq SR, Ahmed D (2016): Monitoring and distribution patterns of pesticide residues in soil from cotton/wheat fields of Pakistan. Environ Monit Assess 188–695:1–12. https://doi.org/10.1007/s10661-016-5668-6
Rashid S, Shah IA, Tulcan RXS, Rashid W, Sillanpaa M (2022) Contamination, exposure, and health risk assessment of Hg in Pakistan: a review. Environ Pollut 301:118995. https://doi.org/10.1016/j.envpol.2022.118995
Riaz G, Tabinda AB, Baqar M, Mahmood A, Mumtaz M, Qadir A, Yasar A, Khorram MS (2018a) Human health risk surveillance through the determination of organochlorine pesticides by high–performance liquid chromatography in water, sediments, and fish from the Chenab River, Pakistan. Anal Lett 51:1245–1263. https://doi.org/10.1080/00032719.2017.1372467
Riaz G, Tabinda AB, Kashif M, Yasar A, Mahmood A, Rasheed R, Khan MI, Iqbal J, Siddique S, Mahfooz Y (2018b) Monitoring and spatiotemporal variations of pyrethroid insecticides in surface water, sediment, and fish of the river Chenab Pakistan. Environ Sci Pollut Res 25:22584–22597. https://doi.org/10.1007/s11356-018-1963-9
Rijal JP, Regmi R, Ghimire R, Puri KD, Gyawaly S, Poudel S (2018) Farmers’ knowledge on pesticide safety and pest management practices: a case study of vegetable growers in Chitwan, Nepal. Agriculture 8:1–11. https://doi.org/10.3390/agriculture8010016
Robinson T, Ali U, Mahmood A, Chaudhry MJI, Li J, Zhang G, Jones KC, Malik RN (2016) Concentrations and patterns of organochlorines (OCs) in various fish species from the Indus River, Pakistan: a human health risk assessment. Sci Total Environ 541:1232–1242. https://doi.org/10.1016/j.scitotenv.2015.10.002
Saad M, Shams DF, Khan W, Ijaz A, Qasim M, Hafeez A, Khan A, Baig SA, Ahmed AN (2017) Occurrence of Selected Pesticides and PCPs in Surface Water Receiving Untreated Discharge in Pakistan. J Environ Anal Toxicol 7:1–7. https://doi.org/10.4172/2161-0525.1000500
Sabarwal A, Kumara K, Singh RP (2018) Hazardous effects of chemical pesticides on human health–cancer and other associated disorders. Environ Toxicol Pharmacol 63:103–114. https://doi.org/10.1016/j.etap.2018.08.018
Saeed MF, Shaheen M, Ahmad I, Zakir A, Nadeem M, Chishti AA, Shahid M, Bakhsh K, Damalas CA (2017) Pesticide exposure in the local community of Vehari District in Pakistan: an assessment of knowledge and residues in human blood. Sci Total Environ 587:137–144. https://doi.org/10.1016/j.scitotenv.2017.02.086
Sana S, Qadir A, Mumtaz M, Evans NP, Ahmad SR (2021) Spatial trends and human health risks of organochlorinated pesticides from bovine milk; a case study from a developing country, Pakistan. Chemosphere 276:130110. https://doi.org/10.1016/j.chemosphere.2021.130110
Sanpera C, Ruiz X, Llorente GA, Jover L, Jabeen R (2002) Persistent organochlorine compounds in sediment and biota from the Haleji Lake: a wildlife sanctuary in South Pakistan. Bull Environ Contam Toxicol 68:237–244. https://doi.org/10.1007/s001280244
Shammi M, Sultana A, Hasan N, Rahman MM, Islam MS, Bodrud-Doza M, Uddin MK (2020) Pesticide exposures towards health and environmental hazard in Bangladesh: a case study on farmers’ perception. J Saudi Soc Agric Sci 19:161–173. https://doi.org/10.1016/j.jssas.2018.08.005
Sharafi K, Pirsaheb M, Maleki S, Arfaeinia H, Karimyan K, Moradi M, Safari Y (2018) Knowledge, attitude and practices of farmers about pesticide use, risks, and wastes; a cross-sectional study (Kermanshah, Iran). Sci Total Environ 645:509–517. https://doi.org/10.1016/j.scitotenv.2018.07.132
Silva V, Mol HGJ, Zomer P, Tienstra M, Ritsema CJ, Geissen V (2019) Pesticide residues in European agricultural soils – a hidden reality unfolded. Sci Total Environ 653:1532–1545. https://doi.org/10.1016/j.scitotenv.2018.10.441
Sohail M, Eqani SAMAS, Podgorski J, Bhowmik AK, Mahmood A, Ali N, Sabo-Attwood T, Bokhari H, Shen H (2018) Persistent organic pollutant emission via dust deposition throughout Pakistan: spatial patterns, regional cycling and their implication for human health risks. Sci Total Environ 618:829–837. https://doi.org/10.1016/j.scitotenv.2017.08.224
Sultan M, Waheed S, Ali U, Sweetman AJ, Jones KC, Malik RN (2019) Insight into occurrence, profile and spatial distribution of organochlorine pesticides in soils of solid waste dumping sites of Pakistan: influence of soil properties and implications for environmental fate. Ecotoxicol Environ Saf 170:195–204. https://doi.org/10.1016/j.ecoenv.2018.11.020
Sultana J, Syed JH, Mahmood A, Ali U, Rehman MYA, Malik RN, Li J, Zhang G (2014) Investigation of organochlorine pesticides from the Indus Basin, Pakistan Sources, air–soil exchange fluxes and risk assessment. Sci Total Environ 497–498:113–122. https://doi.org/10.1016/j.scitotenv.2014.07.066
Syed JH, Malik RN (2011) Occurrence and source identification of organochlorine pesticides in the surrounding surface soils of the Ittehad Chemical Industries Kalashah Kaku, Pakistan. Environ Earth Sci 62:1311–1321. https://doi.org/10.1007/s12665-010-0618-z
Syed JH, Malik RN, Liu D, Xu Y, Wang Y, Li J, Zhang G, Jones KC (2013) Organochlorine pesticides in air and soil and estimated air–soil exchange in Punjab, Pakistan. Sci Total Environ 444:491–497. https://doi.org/10.1016/j.scitotenv.2012.12.018
Syed JH, Alamdar A, Mohammad A, Ahad K, Shabir Z, Ahmed H, Ali SM, Sani SGAS, Bokhari H, Gallagher KD, Ahmad I, Eqani SAMAS (2014a) Pesticide residues in fruits and vegetables from Pakistan: a review of the occurrence and associated human health risks. Environ Sci Pollut Res 21:13367–13393. https://doi.org/10.1007/s11356-014-3117-z
Syed JH, Alamdar A, Mohammad A, Ahad K, Shabir Z, Ahmed H, Ali SM, Sani SGAS, Bokhari H, Gallagher KD, Ahmad I, Eqani SAMAS (2014b) Pesticide residues in fruits and vegetables from Pakistan: a review of the occurrence and associated human health risks. Environ Sci Pollut Res 21:13367–13393. https://doi.org/10.1007/s11356-014-3117-z
Tahir S, Anwar T, Ahmad I, Khan D (2014) Effects of washing on concentration of residual pesticides in salad vegetables. Int J Biol Biotechnol 11:655–659
Tariq MI, Afzal S, Hussain I (2004) Pesticides in shallow groundwater of Bahawalnagar, Muzafargarh, D.G. Khan and Rajan Pur districts of Punjab, Pakistan. Environ Int 30:471–479. https://doi.org/10.1016/j.envint.2003.09.008
Tariq MI, Afzal S, Hussain I (2006) Degradation and persistence of cotton pesticides in sandy loam soils from Punjab, Pakistan. Environ Res 100:184–196. https://doi.org/10.1016/j.envres.2005.05.002
Tariq MI, Afzal S, Hussain I, Sultana N (2007) Pesticides exposure in Pakistan: a review. Environ Int 33:1107–1122. https://doi.org/10.1016/j.envint.2007.07.012
Tehseen WM, Hansen LG, Wood SG, Hanif M (1994) Assessment of chemical contaminants in water and sediment samples from Degh Nala in the Province of Punjab, Pakistan. Arch Environ Contam Toxicol 26:79–89. https://doi.org/10.1007/BF00212797
Ullah R, Asghar R, Baqar M, Mahmood A, Ali SN, Sohail M, Schäfer RB, Eqani SAMAS (2018) Assessment of organochlorine pesticides in the Himalayan riverine ecosystems from Pakistan using passive sampling techniques. Environ Sci Pollut Res 1:1–15. https://doi.org/10.1007/s11356-018-3987-6
Ullah R, Nawab K (2019) Pesticides use in Khyber Pakhtunkhwa Province Pakistan: present scenario. Int J Biosci 14:197–208. https://doi.org/10.12692/ijb/14.2.197-208
Ullah S, Faiz P, Aamir M, Sabir MA, Mahmood Q (2019) Occurrence and spatio-vertical distribution of DDT in soils of abandoned DDT factory area, Amangarh, Pakistan. SN Appl Sci 1(817):1–9. https://doi.org/10.1007/s42452-019-0830-8
USEPA (2000) USEPA Guidance for Assessing Chemical Contaminant, Data for Use in Fish Advisories: Fish sampling and analysis (3ed ed.), 1, Office of Water. Washington, DC, EPA 823–R–95–007
Verheyen J, Stoks R (2019) Current and future daily temperature fluctuations make a pesticide more toxic: contrasting effects on life history and physiology. Environ Pollut 248:209–218. https://doi.org/10.1016/j.envpol.2019.02.022
Waheed S, Halsall C, Sweetman AJ, Jones KC, Malik RN (2017) Pesticides contaminated dust exposure, risk diagnosis and exposure markers in occupational and residential settings of Lahore, Pakistan. Environ Toxicol Pharmacol 56:375–382. https://doi.org/10.1016/j.etap.2017.11.003
Wang R, Yuan Y, Yen H, Grieneisen M, Arnold J, Wang D, Wang C, Zhang M (2019) A review of pesticide fate and transport simulation at watershed level using SWAT Current status and research concerns. Sci Total Environ 699:512–526. https://doi.org/10.1016/j.scitotenv.2019.03.141
Wumbei A, Houbraken M, Spanoghe P (2019) Pesticides use and exposure among yam farmers in the Nanumba traditional area of Ghana. Environ Monit Assess 191:1–16. https://doi.org/10.1007/s10661-019-7449-5
Yasmeen H, Qadir A, Mumtaz M, Eqani SAMAS, Syed JH, Mahmood A, Jamil N, Nazar F, Ali H, Ahmad MS, Tanveer ZI, Zhang G (2017) Risk profile and health vulnerability of female workers who pick cotton by organanochlorine pesticides from southern Punjab, Pakistan. Environ Toxicol Chem 36:1193–1201. https://doi.org/10.1002/etc.3633
Zhang L, Lecoq M, Latchininsky A, Hunter D (2019): Locust and grasshopper management. Annu Rev Entomol 1-23 https://doi.org/10.1146/annurev-ento-011118-112500
Zhang M, Zeiss MR, Geng S (2015) Agricultural pesticide use and food safety: California’s model. J Integr Agric 14:2340–2357. https://doi.org/10.1016/S2095-3119(15)61126-1
Zia MS, Khan MJ, Qasim M, Rahman A (2009) Pesticide residue in the food chain and human body inside Pakistan. J Chem Soc Pak 31:1–9
Acknowledgements
Sajid Rashid was the recipient of the scholarship awarded by the China Scholarship Council (CSC No. 201929180010), which supported his study at Beijing Normal University.
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This work is supported by the China Scholarship Council (CSC No. 201929180010).
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Sajid Rashid: conceptualization, writing—original draft, Haiou Huang: conceptualization, supervision, funding acquisition, writing—review and editing, Wajid Rashid: methodology, writing—review and editing, Roberto Xavier Supe Tulcan: software, mapping.
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Rashid, S., Rashid, W., Tulcan, R.X.S. et al. Use, exposure, and environmental impacts of pesticides in Pakistan: a critical review. Environ Sci Pollut Res 29, 43675–43689 (2022). https://doi.org/10.1007/s11356-022-20164-7
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DOI: https://doi.org/10.1007/s11356-022-20164-7